摘 要 ：目的：研究大孔吸附树脂富集丹参中总酚酸的工艺条件及参数。方法：以丹参总酚酸含量为考察指标,筛选了不同型号的树脂,确定了H103型树脂为最佳树脂,并优选H103型树脂富集丹参总酚酸的最优条件。结果：取127 mL H103树脂,树脂径高比为1∶6,上样液质量浓度为1.25 g·mL-1。最大上样量为0.67 BV,吸附和洗脱流速均为2 BV·h-1,上样吸附后,用水洗4 BV后,用含有1％氨水的80％乙醇洗脱,用量为4 BV。结论：此法可较好地富集丹参中的总酚酸。
Abstract:Objective: To study the technological parameters of the purification process of Depsides in Salvia miltiorrhiza with macroporous resin. Method: The adsorptive characteristics and eluting rameters of the process were studied by taking the content of depsides as index. Result: 85 mL of extractive of depsides (1.25 g·mL-1) was purified with a column of macroreticular resin (Φ30 mm,127 mL) and washed with 4 BV of distilled water, the eluted with 4 BV of 80% ethanol (1% ammonia). Conclusion: This process of applying macroporous resin to adsorb and purify depsides in S. miltiorrhiza is feasible.