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期 刊 ：中国中药杂志 2003年 28卷 02期 页码：130.

关键词：水提液；除杂；

Keywords:water-extraction, removing impurity,

摘 要 ：目的:探讨大孔吸附树脂法、壳聚糖澄清法和乙醇沉淀法在固天泉胶囊水提液中除杂结果。方法:比较大孔吸附树脂法、乙醇沉淀法和壳聚糖澄清法所得到的浸膏得率及浸膏中人参皂苷Rg₁,Re的定性分析以及Rg₁、阿魏酸含量测定考察。结果:乙醇沉淀法所得的浸膏得率为17.2％,壳聚糖澄清法所得的浸膏得率为12.8％,大孔吸附树脂法所得的浸膏得率为3.1％,3种方法均能够较好地使水提液澄明,且后两者还能够在降低浸膏得率、保留有效成分、保证制剂稳定性方面优于前者,并能缩短生产周期,降低成本。结论:壳聚糖澄清试剂法较适合于固天泉胶囊水提液除杂工艺。

Abstract:Objective: To study the result of removing impurity from water-extraction of Gutianquan-capsule with macro-reticular absorbing resin,chitosans clarification, water-extraction and alcohol-precipitation methods. Method: Coefficient of Unguent of macro-reticular absorbing resin,chitosans clarification method, water-extraction and alcohol-precipitation methods were compared, and qualitative assay of Ginsenoside Rg1 ,Re, and snide measurement of Ginsenoside Rg1,Ferulic acid, and stability experiment were made. Result: Coefficient of Unguent of water-extraction and alcohol-precipitation method was 17. 2% , Coefficient of Unguent of chitosans clarification method was 12.8% , and macro-reticular absorbing resin method was 3.1%. They could clarify liquor of water-extraction. Conclusion: Chitosans clarification method is suitable for process of Gutianquan-capsule.

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