Abstract:Heat-cleaning and detoxifying drugs and fire-purging drugs used in combination have been proved able to restorethe endotoxin-induced deviant of NCT, blood viscosities,PTT and fibrinolytic activity,and reduce the blood content ofboth endotoxin and PGE_2 in rabbits. In addition,the combination can also decrease the pes swelling percentage in ratsas well as evans blue extravasation volume in mice,In practice,however,it should be noted that the bitter and coldqualities of these two kinds of drugs may be harmful to health.