Abstract:The anti-free radical effects ofwater extracts of crude Astragalus menghoftcus (CAWE) and honey-fried As-tragalus mongholicus (HAWE) have been studied- Both extracts have similar effects in scavenging 0. 2 in Xan/Xosystem. The effect of CAWE is stroger than that of HAWE in scavenging reactive oxygen species (ROS) producedby PMA and stimulated by PMN and also in scavenging OH engendered by Fentons reaction. This suggests thatfrying process may decrease the ROS scavenging activities of Astragalus mongholicus.