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期 刊 ：中国中药杂志 1995年 20卷 04期 页码：235.

关键词：四逆汤；心肌缺血；脂质过氧化；量效；时效；

Keywords:Sini Decoction, myocardial lschemia, lipid peroxidation, dose, effect, time effect,

摘 要 ：四逆汤全方可显著降低缺血心肌MDA含量,组成四逆汤的各单味药除干姜外,附子、甘草也有一定的抗胎质过氧化作用,但不及全万。本实验条件下,在0.05～0.2ml/20g剂量范围内和0.1ml/(20g·d)用药2～7天,四逆汤抗脂质过氧化作用显著。

Abstract:The complete Sini Decoction can significantly reduce the content of MDA in isehemic myocardium. Single ingredients of the deceetion,such as Radix Aconoti Praeparata or Radix Glycyrrhizae,except Rhizoma Zingiberis,also havesimilar effect but inferior to that of the complete decoction. Under the present conditions of experiment, anti-lipid peroxidation of Sini Decoction is significant at doses ranging from 0.05 to 0.2ml/20g. administrated for 2～7days at0.1ml/(20g·d).

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