期 刊 :中国中药杂志 1996年 21卷 12期 页码:751.
关键词:野百合碱;肺动脉高压;粉防己碱;
Keywords:monocrotaline, pulmonary hypertension, tetrandrine,
摘 要 :大鼠腹腔注射野百合碱50mg/kg.3周后形成肺动脉高压并伴有右室肥大。粉防已碱每次10mg/kg及15mg/kg,每日2次灌胃能抑制野百合碱形成肺动脉高压及右室肥大的作用。
Abstract:Pulmonary hypertension and right ventricular hypertrophy in rats were developed 3 weeks after administration of monocrotaline 50mg/kg ip. Tetrandrine 10mg/kg and 15mg/kg bid po could prevent the above-said effects produced by monocrotaline.
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