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期 刊 ：中国中药杂志 1989年 14卷 02期 页码：38.

关键词：大花罗布麻；膜电位；心肌收缩力；希氏束电图；

Keywords:Apocynum hendersonii, membrane potential, myocardiac contractility, His bundle electrogram,

摘 要 ：实验发现大花罗布麻对离体兔心肌标本有钙拮抗剂样的作用,使动作电位时程缩短、心肌收缩力减弱。对部分除极纤维的自发或激发电活动抑制作用明显。在整体动物实验中,观察到对窦房结起搏活动、房室传导的抑制。

Abstract:Calcium antagonist-like effect of Apocynum hendersonii on myocardiac preparations was observed in the present experiments. The action potential duration and contractility were decreased. Automatic or exciting activity in partially depolarized fibers was considerably inhibited or concealed. Observation in vivo showed that pacemaking in SA node and conducting in AV node area were inhibited.

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