Abstract:We have studied the effects of Liuwei Dihuang decoction(LDD)and its compositions on blood sugar and glycogen in mice, and found that Sanbu, Shanzhuyu-Danpi and Shanyao-Fuling matched pairs can reduce the level of blood sugar, while LDD, Sanbu, Shudi-Zexie and Shanzhuyu-Danpi matched pairs can increase the content of glycogen in liver. The present study is only a preliminary research ou the effects of LDD and its compositions on the metabolism of sugar in the body.