Abstract:The antidotal effect of four extracts from Stenoloma chusanum on acute poisoning of mice caused by arsenic and ammonium chloride was observed. The result shows:extracts B and C can reduce the mortality of mice remarkably, while extract C can raise the tolerance of mice by raising their LD50 from 31.1±4.3 mg/kg to 38.2±5.9 mg/kg, In the case of the mice poisoned by ammonium chloride, the four extracts can also reduce the mortality,but make no significant difference as compared with the control group statistically(P>0.05).