---

期 刊 ：中国中药杂志 1991年 16卷 10期 页码：617.

关键词：炙甘草注射液；抗心律失常；

Keywords:Zhigancao (Prepared Licorice) injection, anti-arrhythmia,

摘 要 ：炙甘草注射液对氯仿,肾上眼素,乌头碱、毒K和氯化钡诱发的动物心律失常均有对抗作用,并能减慢心率、延长P-R和Q-T间期,对抗异丙肾上腺素的正性心率作用。其腹腔注射的半数致死量为41.2g/kg。

Abstract:Zhigancao injection can antagonise the arrhythmia induced by chloroform, adrenaline, aconitine, strophanthine K and barium chloride, slow the heart rate, prolong P-R and Q-T intervals and antagonise the positive chronotropic response induced by isoprenaline. The LD₅₀ of Zhigancao injection is 41.2g/kg in nice by intraperitoneal.

---