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期 刊 ：中国中药杂志 1989年 14卷 12期 页码：42.

关键词：芦荟；谷丙转氨酶；CCl肝损伤；

Keywords:Aloe, sGPT, CCl intoxication,

摘 要 ：芦荟注射液、芦荟总甙及总甙中分离的结晶Ⅲ能降低CCl₄、硫代乙酰胺和D-氨基半乳糖引起的小鼠或大鼠谷丙转氨酶升高,对CCl₄引起的肝细胞损伤有保护作用。狗的长期毒性试验表明,芦荟注射液毒性很低。临床治疗乙型慢性肝炎38例,有效率86.8%。

Abstract:The injection(10～15ml/kg/d, ip×4), total glycoside (125～225mg/kg/d, ip×(3～4); 600mg/kg/d, ig×3) and crystal Ⅲ(120mg/kg/d,ip×4) of Aloe vera var. chinensis were found to be effective in lowering the elevated sGPT induced by CCl₄, thioacetamide and D-aminogalactose in mice or rats. It was also observed that these agents could protect hepatic cells from the CCl₄-induced injury. When dogs were given in with Aloe injection of 0.1 ml/kg/d×180, no toxicity was noted. The total effective sGPT-lowering rate of Aloe injection on 38 patients of chronic hepatitis with positive HBsAg was 86.8%.

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