Research Progress on the Crystal Structure of D-amino Acid Oxidase Small Ubiquitin-Like Modifier Conjugating Enzyme with Active Site Mutation Acts as Dominant Negative Inhibitor of SUMO Conjugation in Arabidopsis Site-directed Mutagenesis of the CpeS of Phycocyanin and Study on the Function with Reconstitution in vivo Effect of active site of Xiangsha Liujunzitang on behavior and injury of hippocampal neurons in depression model mice Study on HPLC chromatographic fingerprint of anti-tumor active site SSCE of Caulis spatholobi