Technology optimization for extracting total favonoids from Gynostemma pentaphyllum by cellulase Optimized preparation of Silymarin Dropping Pill by a central composite design-response surface method Optimization for purifying technology of Nelumubinis Plumula extract with chitosan by comparison of orthogonal design and response surface method Optimization for preparation technology of baicalin-phospholipid complex in situ nasal gel by central composite design-response surface method Technology optimization for extracting total favonoids from Gynostemma pentaphyllum by cellulase Optimization for purifying technology of Nelumubinis Plumula extract with chitosan by comparison of orthogonaldesign and response surface method Optimization for preparation technology of baicalin-phospholipid complex in situ nasal gel by central composite design-response surface method