Determination of osthol in LOTIO FRUCTUS CNIDII COMPOSITA by RP-HPLC Studies on the Quality of Fructus Cnidii——Comparison of Antibacterial Action Simultaneous determination of 5 active components in fructus cnidii by HPLC Chemical change in compatibility of Radix Sophorae Flavescentis with Fructus Cnidii