Two new C 27 steroidal glycosides, named ophiopojaponin A (1) and B (2), together with two known ones, were isolated from the tubers of the famous traditional Chinese herb Ophiopogon japonicus Ker-Gawl. The spectroscopic and chemical evidence revealed their structures to be pennogenin 3-O-［2′-O-acetyl-α-L-rhamnopyranosyl (1→2)］-β-D-xylopyranosyl (1→3)-β-D-glucopyranoside (1), 26-O-β-D-glucopyranosyl-(22ξ, 25R)-3β,14α,22ξ, 26-tetrahydroxyfurost-5-ene 3-O-α-L-rhamnopyranosyl (1→2)-β-D-glucopyranoside(2), diosgenin 3-O-［α-L-rhamnopyranosyl (1→2)］-β-D-xylopyrano-syl (1→3)-β-D-glucopyranoside (3) and ruscogenin 1-O-［α-L-rhamnopyranosyl (1→2)］-β-D-xylopyranosyl (1→3)-β-D-fucopyranoside (4).
川麦冬中的新C27甾体甙
戴好富1 周俊1* 谭宁华1丁中涛2
（1. 中国科学院昆明植物研究所植物化学开放实验室，昆明650204；2. 云南大学化学系，昆明650091）
摘要： 从百合科植物川麦冬（Ophiopogon japonicus Ker_Gawl.）块根中分离得到4个C27甾体甙类化合物，其中两个为新化合物：ophiopojaponin A (1)和B (2)。它们的结构通过波谱和化学方法鉴定为：pennogenin 3-O-［2′-O-acetyl-α-L-rhamnopyranosyl (1→2)］-β-D-xylopyranosyl (1→3-β-D_glucopyranoside (1), 26-O-β-D-glucopyranosyl-(22ξ, 25R)-3β, 14α, 22ξ, 26-tetrahydroxyfurost-5-ene 3-O-α-L-rhamnopyranosyl (1→2)-β-D-glucopyranoside (2), diosgenin 3-O-［α-L_rhamnopyranosyl (1→2)］-β-D-xylopyrano-syl (1→3)-β-D-glucopyranoside (3) and ruscogenin 1-O-［α-L-rhamnopyranosyl (1→2)］-β-D-xylopyranosyl (1→3)-β-D-fucopyranoside (4)。
关键词： 川麦冬；百合科；C27甾体甙
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