Abstract:In the prevention of sepsis and some other severe bacterial diseases， the traditional antibiotic therapy appeared more and more serious bacterial resistance， antibiotic residues and other problems， therefore phage therapy and some other non-anti therapies have received widespread attention. Here we elucidate and evaluate the classification and biological characteristics of phages， the clinical results of the application of phage in the treatment of animal and human bacterial infections， and also analyze the advantages and disadvantages of phage therapy. Phage therapy has shown many incomparable advantages， which is a promising alternative to antibiotics for bacterial pathogens.