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Extraction process of flavonoids from Momordica charantia

超临界CO2流体萃取苦瓜总黄酮工艺及其抗氧化活性



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ChineseJournalofBioprocessEngineering
Vol.8No.1
Jan.2010
doi:10.3969/j.issn.1672-3678.2010.01.013
OPQI
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ExtractionprocessofflavonoidsfromMomordicacharantiaL.with
supercriticalcarbondioxideanditsantioxidantactivity
XIEJianhua1,SHANBin2,PENGYun2
(1.StateKeyLaboratoryofFoodScienceandTechnology,NanchangUniversity,Nanchang330047,China;
2.DepartmentofFoodScienceandTechnology,YingdongColegeofBiologicalScience,ShaoguanColege,Shaoguan512005,China)
Abstract:Responsesurfacemethodologywasusedtodeterminetheoptimumprocessingconditionsforsu
percriticalcarbondioxideextractionofflavonoidsfromMomordicacharantiaL.Basedonsinglefactorex
periments,theefectsofpressure,temperature,andextractiontimewerestudiedwiththecentralcom
positedesignandtheirinteractionsontheyieldofflavonoidswerealsoinvestigated.Theinfluenceofthe
orderwaspressure,temperature,andextractiontime.Thepolynomialquadraticequationwassolvedby
SASsoftwarecombinedwiththeresponsesurfacemethodology.Optimumconditionswerepressure334
MPa,temperature46℃,extractiontime532min,andabsoluteethanolasentraineronasfolows:the
ratioof40mL/g.Theextractionratewasupto843%.Thescavengingabilityon1,1diphenyl2-
picrylhydrazylreached931%,asreferencedwithclearancerateofvitaminCat1mg/mL.
Keywords:flavonoids;MomordicacharantiaL.;supercriticalcarbondioxide;extraction
  

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