Abstract:Bacterial wilt was caused by Ralstonia solanacearum. The Type III secretion system (T3S ) and TypeⅡsecretion system (T2S ) that directly translocated effector proteins into the host cells were essential for the development of disease. There were several ways to improve disease resistance of crops to bacterial wilt, such as, transgenic technology, breeding resistant cultivars, biocontrol, and so on.