Abstract:This objectives of the present study are to break the limitations in preventing and controlling Astragalus root rot fungus by chemical agents(especially pesticides) and to develop green measures in preventing and controlling diseases of Chinese herbal medicines. Using Fructus cnidii, Rhizoma anemarrhenae extracts drug-containing medium, and sterile water as control, after inoculating with Astragalus root rot fungus, the inhibitory effects of these two kinds of traditional Chinese medicine on Astragalus root rot fungus-Fusarium oxysporum were studied in vivo. The results showed that kinds of traditional Chinese medicine extracts exhibited different impacts in inhibiting Astragalus root rot fungi. Analysis of variance results indicated that from the point of view of both the types and concentrations of extracts of two Chinese medicines,F.cnidii showed better performance in preventing and controlling Astragalus root rot fungi, Cnidium combat the effect of Astragalus root rot fungus is more obvious, with significant level, the highest inhibition rate 96.13%.