Abstract:To evaluate resistance of winter wheat cultivars currently grown in Henan Province, China to Wheat yellow mosaic virus (WYMV), the resistance of 62 commercial wheat cultivars was tested in a disease nursery at Xiping, Henan Province in the years 2006 to 2010. Plants were also tested using an indirect ELISA in the laboratory and the influence of disease severity on wheat yield and grain quality was investigated. Of the cultivars tested, only Xinmai 208 appeared to be immune to WYMV and nine cultivars (14% of those tested) were resistant: Yumai 70-36, Fanmai 5, Fumai 936, Shandong 95519, Yumai 70, Gaoyou 503, Yumai 9676, Zhengmai 366 and Shaanmai 229. Thirteen cultivars (21% of those tested) were moderately resistant (Puyou 938, Lankaoaizao 8, Xinyuan 958, Huapei 2, Wenyou 1, Yumai 18, Zhengmai 9023, Yumai 47, Yunong 201, Yanzhan 4110, Yumai 36, Bainong 878 and Yumai 49-198) and the remaining 39 cultivars (63% of those tested) were susceptible. In studies of 48 cultivars, increasing disease severity decreased grain yields, spike numbers and 1000-grain weights. 9.6% yield was lost when disease severity was grade 1, and 30.3% and 33.5% yield was lost when the disease severity was grade 2 and 3 respectively.