The toxicity of lambda-cyhalothrin、beta-cypermethrin plus emulsion, E,C、alathion、azadirachtin and xylene at the different concentration and treating time was studied with five insect cell lines, applying Blackman viability analysis instrument. The results showed that the four types of pesticides had toxic effect on the cell lines, while xylene at three concentrations had no obvious toxic effect on the cell lines. The tests indicated that azadirachtin was significantly more toxic than other pesticides, then in turn were beta-cypermethrin plus emulsion,E,C, alathion, and lambda-cyhalothrin. The five cell lines responded differentially to the same testing concentration of same pesticide, and had different sensitivity to the chemicals. Amonge them, cell line Sf 9 was more sensitive than other cell lines, followed in turn by NIAS-MaBr-85,SL2, NIH-SaPe-4 and C6/36. The results indicated that the sensitivity of insect cell lines to the pesticides was in accord to the mechanism of pesticides, and the insect cell lines used for the determination of pesticide cytotoxicity is feasible.
全 文 :!!"
" !
!
#
# $ % %
$
!
%
& ( )
&()*+(, &(-.,) &(*(,)
./01!"!*/1!
,234!# $ % %
RST7
8
VU<4V@W¶r(Y
!
3
5
ç
%!#
5
!
5
â
%!#
5
è(4
%!#
5
é
5
^
%!#
5
U
5
$
#
5
é
5
ê
#
"%1
\X&()lmF¿Ý^almþ
5
^_
78$##!$ #1
X¯&å¿Ý^a¹y
ñRS*+,
5
^_
78$##!#
#$%
5
çF
$
^a4Ðà
$
DÞ
$
ý4
$
hÔi
&()*
! &"%>1"$ &"7"555
+,-./
!,555
+01*
!%$$% ?"!>>"#$%%#$! ?$%># ?$>
¦§¨#
#$$9 ?%$ ?##$
©ª¨#
#$%$ ?$> ?%>&
«¬®
&fÑ;¼(lÒ
"! 6^># &
!Ê¥ÄÅÆÇ
&
A#-.=,#;#)%-)0/)-2@.(.&"6@%&%&L($(%@ &"8 T).#$%6#2?()#.T)0=$#07@ 1&;#O#.%($(0#.
APGEFKJE
%!#
5CDEFMJEF
%!#
5BJEFZDJTDEF
%!#
5YG+G/
%!#
5-JN I/EF
#
5YGMGE
#
"%1=&&1%*/ ?2(.(0(&$:=&$0%*&?2&*(!@3#5702A.2, 78$##!$ #17&)819$%1($%)$:@0+(.51(.2, 12C
4(.+.>1(.$2 $:=&$0%*&?2&*($:-(1($%&(%)3CA.2.(%1(.$25702A.2, 78$##!#
/7.%,-$%5+PDH/WJOJHS/T0G
H/WJOHPGE /HPD32DQHJOJRDQ! HPDE JE HN3E LD3DVDHG^OS2D3
GOO/3R H/HPD
B#@ C&,0.5OSH/H/WJOJHS$ JEQDOHOD00JEDQ$ 2DQHJOJRD$ WS0DED$ TGHG0JHS3GHDQ
55
°
#$
¹Ö
7$
$(
i3GOD
VðZ!³âóh
wÞ(?^a4Ðà6!
"i3GOD!%97##!
/ÒQ²
$?lmn(e
!
^a4Ð+¡4ÐàVð
%
µpn
%
^a4еp?
ñçå
:ZmE?{e
!
^a4Ðtabê^ñù)
%
D
)ÖM)?â-.
"
C!Ãç
!#$$!$
µËµ
ç
!#$$7$ YG3G3/QOP &(1+4!%99##&
®:
!
7¹º
+<
8$$
[»^a4Ðà:6Vð
"-SEE!#$$%#!
%$$
[^a4Ðt^ñM)nù)?lm
"
PqÑç
!#$$##!
ñ^a4Ðçi)ÞÖ
M:;úçF?ðjçFijàô|(e
!
&
©
#$
¹Ö
7$
$(db©<)Ç{¼Z^a
4Ðíjop1DÞ?çFçi
"YJHQNPGQPJ&(1+4!
%9"$$
¯µç
!%997#! ZGHD3P/NQD"%978#
âîlm
Z
BB+
7ÌÍÞ(4Ðà?@A
$ M/QPJRG
"%9"9#
lmZ<=Þ?ºa>7íj4Ðê
()ÖMEq@Þ?@A
$ &HJ2GE/UJO
ç
"%99$#
âî«ñZ
Y++
iwZ¯5àv±
7é÷Í
"B&+.$(/.5.%&&*2#
4Ðà?çF
$
IGPJ/NJR
ç
"#$$"#%&G0DP\GRDP
ç
"#$$##
³"ZN
ºÖDÞç76ê÷Í
" -<$C$<(&%1 :%0,.<&%C1#
4Ð
à
&T?9
?4Ðç;
$
£ý
!BGQ
ç
"#$$7#
ñD
Þ7jýØp1`4Ðà?çF!çiDÞ7
j?@A
&
XÔ¡
å?lmdb:üï
!
öE
[d\
ñ
Y++
çi
!
¹Eç
"#$$8#
iw
Zºa>7¯Ì4Ð?çF
$
XKç
"#$$>G#
l
m³"Z
9
"Ýú7Â÷Í
"!%$C&2.1
+.(0%1#
4Ðà
&-?%
4Ð#J2j?@A
$
ØèÓ
ç
"%99"G$ %99"V#
ñ®{?
Y++
çiZ-|
%
¥ý
%
ý4ç<=>ºa>7¸9Î
"!.&%.
%1<1
4Ðàn¯Wa
"B&+.*$5&%<1 1A.,&%1#
4Ðà
?çF
$
¯µç
"%997#
ñ¸èa
"
¸9Î
#
4Ð
çiý«Ï
%
-|
%
¥ýÖý4ç?çF
&
DÞ?:jMçiØ#I
!
F
!
ö^a
5!
!
# µ
5
=ç
ñDÞ7
8
^a4Ðà?çFiwÖqz
7Þ>?ST;ö#
%
/0
%
^aÞàç?9?@
AüE
!
Ú
ñ^a4Ð{¼ºa>?ØÄnçF
iwLû<;Þ5
%
S
%
X
%
Ø#{
%
f
ñØÄ
%
+op
%
#OçÌS
!
è
ZÞáMiw?-K
"
PqÑç
!#$$#$
Øè
Óç
!%997#&
&lm
ñ
@0GO]
ªiwZ
!
ñDÞÖý4¡-.`CK
7!ÝGÏ®nÖÏ®?
8
^a4Ðà?ç
F
!
rB-.DÞ7^a4Ð?Æñ=
!
¥
ñ
^a4Ðà{¼DÞ:;ØÄvw«x
&
FG
yzb
%1%5
02LM/NO
5
4Ðà
6
â!Ý
GÏ®
%#
â!ÝÖÏ®
"
%#!
¥&lmþ^
a4ЫG¥
!
«23
%$_ C@& "TDHG0
V/UJEDQD3N<#!
#
2c
ª¥
716! 8
4Ðà¡
#> :
1ss
!8 b"
Þ(
%
î
&
m
FG
íx4V
:-7RFG:>#().#$%$#22()#."&,%#.%
4Ðà]Ü
D00JEDEG
YDRJN<
»ÉÐ
&-# R%$$#
&OPEDJRD3
ºÂÙÑ
7r67 3&C&1+9$<.*(07r67 BY)Y
oÐ
*(c^&GgD^! -1%*$1,1 <&%&,%.2&*(c^&GgD^! YY
û ÷ Í
*(,& Y^G@I^>8 G1A&(%1 9%1.*1&*(,&^
YG@I^>8
YY
6ê÷Í
&T9 -<$C$<(&%1 :%0,.<&%C1 &T9 +*Y^Cc
"
%5
-.7
&-#
4Ð?çF
CJF4%5SH/H/WJOJHSJERNODR VSRJTD3DEHH3DGH
0 2 P 1 / Q R 2 + H S
5
D Þ
#8 F,-
?%
óÿÒ_ý
"
q!þO<ºf$
#%
%$_
ýó
,
ç)Ð
"
z<9%¯DÞ<ºf$
#%
!8_
ÙÖhA
"
à¶âTdeDÞO<ºf$
#%
$16_
=Ó9
"
TU\(M<ºf$
#&
<=
>
ý4
!
Xqzù>
&
!
DÞÖý4/
$1##
#
<
<=>ûÒÒ
x_Òx
!
Û×`ÙWÞ
%$$
¸?OÆl
&
%165
TU<=/pqä(
5
Ê.³4Ðà
l~
!
Ññ
"#8 O<
#
#
qß
%$ <-&
¡+
?«xK
!
ÊDÞÖý4OÆlqr
%$$! #$$!
6$$
#
-
~
%$ <-
l!
ì¢}¥
$1%!
$1#!$16
#
-,<-
?%
!
jź7 ³`
&
:Ö3
ðDÞÖý4
8!#!!!>!"# P
!
/
@0GO]
Ð:Fqzªiw¢:FÖ4ЯN
!
k:4Ð
nÔ4Ð
!
Ñâ¬Þiw
%$$
î
!
ª_!p°=k
ÿ4Ð:F?C
!
ª_àá+*¥
q7_&
&l
m4Ð:F5ÿ61f_kÿ¡
-.?hÔi
&
hÔi
"_# h"
:4Ð:F
?
4Ð
:F
#r
:4Ð:F
d%$$_
ñ
&g&&
!p
BNEOGE
[RÊü7¤
Ö4Ð{¼[RÊü
&
%1!5
g,U
5
8!#!!!>!"# P
qr¡
*J]/E )-(g&)+&%$$
NÚMzÖ¢j à
á1¨¬4ЯNÖ=N
!
j[\4ЯN)
8
&
DG
³b(Y
#1%5!
µP1/|VWÕ
&-#
LM+TU
5 !
DÞ7
&-#
4Ð?MIM-.P0?@A
!
è
DÞ}n?.3
!
hÔi.E
!
¢\ç
6>%
& ( )
!"
"
5
FQE?ù=Ó9
!
=Ó9
$16
#
-,<-
?%
#! P!
hÔi=
>"1##_&
¢îqr¥ýó
,
ç)Ð
%
ÙÖ
hAÖóÿÒ_ý
&
ý4¡
8!#! P
74
ÐMI<³@A
!
¢ò74ÐMIÛ@A
&
7 `4Ð$3~èÆ<³@A÷4ÐMI
ý
!!> P
6ï¤.I
"
"
%#&
z¨¬:
&-#
4Ð-6MI
!
¯N
[¥®¯
!
E2³
&
ý4ÖóÿÒ_ý
?4ЯN8-_
!
¢ò
6
DÞ4Ð
¯N<8
"
##!
j¤¥4ÐÔ·
!
ÊË-2
!
> . [
!
6 |
& $1%
#
-,<-
?%
Ù Ö h A
#! P
Ö
$1#!$16
#
-,<-
?%
8 P
ñ
6ï¤E-_oú
$ $16
#
-,<-
?%
=Ó9
?4ÐhÔiüý
!#! P
«&Û64Ð¥
¡
!
Í
"
"´$
?
%*7#&
m
DG
·¸TU7
1?D
4V±]@AB
!
:-7RDGA&,<>&2&5($-2$>-)5#.&"%>#1?D =)0#,0(""#,#)%%,#-%;#)%
+3DGH
HJ
B3NFO/EODEH3GHJ/Er"
#
-,<-
?%
#
óÿÒ_ý
-G
,
ç)Ð
@DHG^OS2D3
,0GHPJ/E
=Ó9
,\GRJ3GOPHJE
ý4
KS0DED
$1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16
X
8 ? ? ? f f f ? ff ff f ff fff ? ? ? ?
#! ? ? f f ff ff f ff ff f ff fff ? ? f ?
!> ? f ? f ff ff ff ff ff ff ff fff ? ? ? ?
"# ? ? ? ? ff ff ff ff ff ff fff fff ? ? ? ?
55
!4ЯN8
Y/32P/30/FJOG0OPGEFD/THPDOD0Q4?
Û8
*/OPGEFD$ f
8³
&0JFPHOPGEFD$ ff
8_
[VJU/NQOPGEFD$ f
ff
8.R
&D3J/NQOPGEFD4
1.
& +PDQG
µP1/|VWÕ
7r67
LM+TU
5 !
DÞ7
7r67
4Ð?MIM³w?@A
!
D
ÞÖy4Ð?hÔi9-¥¡_
?¬;/à
!
У㤥ý{op1
ýhÔi
&
ç F Q E ? ù = Ó 9
!
= Ó 9
$16
#
-,<-
?%
%8 P
hÔi=
>$1>8_&
¢îq
r¥ÙÖhA
%
óÿÒ_ýÖýó
,
ç)Ð
&
ý4
¡ý
8 P
74ÐMI<³@A
!
¢ò
g74ÐMIM@A
$
7 `4Ðê.
I
"
"
##&
"
#5
-.7
7r67
4Ð?çF
CJF4#5SH/H/WJOJHSJERNODR VSRJTD3DEHH3DGH
z¨¬:
7r67
4Ð-6MI
!
¯N¥[¯
%
¯
!
ºqÍÎMI?4Ð¥*®
¯
&
ý4?4ЯNy7 «&³h
!
¢
ò4ЯNï¤8
"
6#!
£ã¤¥
4ЯNÞ®¯
!
4кº-ä
!
4Ð>-_
!
ï¤ÅY
!
>.[
&
¢\ÙÖhA
$1#!
$16
#
-,<-
?%
8 P
"
"´$
?"*%##&
!>%
5!
!
# µ
5
=ç
ñDÞ7
8
^a4Ðà?çFiwÖqz
m
HG
·¸TU7
6YeHY
4V±]@AB
:-7RHGA&,<>&2&5($-2$>-)5#.&"%>#6YeHY =)0#,0(""#,#)%%,#-%;#)%
+3DGH
HJ
B3NFO/EODEH3GHJ/Er"
#
-,<-
?%
#
óÿÒ_ý
-G
,
ç)Ð
@DHG^OS2D3
,0GHPJ/E
=Ó9
,\GRJ3GOPHJE
ý4
KS0DED
$1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16
X
8 ? ? ? ? ? f ? ff fff ? f fff ? ? f ?
#! ? ff ff f ff ff f ff ff f fff ff ? ? ? ?
!> ? ? f ? f ff f ff ff ff ff f ? ? ? ?
"# ? f f ? ? ff f ff ff ff ff f ? ? ? ?
#165!
µP1/|VWÕ
*(c^&GgD^!
LM+TU
5
=Ó9
%
ýó
,
ç)Ð
%
ÙÖhA7
*(c^&GgD^!
4
Ð?MIM-.P0?@A
!
-¤ïèDÞ}
?.3hÔi.E?/0
!
ÐyhÔ
i9Û_¬;/à
&
¢\çFQE?ù=Ó
9
!
=Ó9
$16
#
-,<-
?%
%8 P!
hÔiý=
9#1"8_&
¢îqr¥ýó
,
ç)Ð
%
ÙÖhA
&
óÿÒ_ýÖ
ý474ÐMI«&Û@A
!
7 `4ÐMIê
"
"
6#&
"
65
-.7
*(c^&GgD^!
4Ð?çF
CJF465SH/H/WJOJHSJERNODR VSRJTD3DEHH3DGH
z¨¬:
*(c^&GgD^!
4Ð-ÍÎM
I
!
¯N¥®¯
%
Õ®¯n5ºq¯
&
óÿÒ_
ý
%
ý4?4ЯNy7 «&³h
!
=
Ó9
%
ýó
,
ç)Ð4ЯNï¤8
"
!#!
£ã¤¥4ÐÔ·
!
4Ð>-_
!
4ÐÔÅ
Y
!
ï¤4ÐÖ¤Ê
!
>.[
&
ÙÖhA
74ЯN@A-_?.<<ï¤E
oú
"
"´$
?%6*%8!
%
?%*6#&
m
IG
·¸TU7
NTSZ1-O#ZI
4V±]@AB
:-7RIGA&,<>&2&5($-2$>-)5#.&"%>#NTSZ1-O#ZI =)0#,0(""#,#)%%,#-%;#)%
+3DGH
HJ
B3NFO/EODEH3GHJ/Er"
#
-,<-
?%
#
óÿÒ_ý
-G
,
ç)Ð
@DHG^OS2D3
,0GHPJ/E
=Ó9
,\GRJ3GOPHJE
ý4
KS0DED
$1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16
X
8 ? ? ? ? ? ff ? ? f f ff fff ? ? ? ?
#! ? ? ? ? ? ff f ? f f ff fff ? ? ? ?
!> ? ? ? ? ? ff ? f f ff fff fff ? ? ? ?
"# ? ? ? ? ? ff ? f f ff ff fff ? ? ? ?
8>%
& ( )
!"
"
5
#1!5!
µP1/|VWÕ
*(,& Y^G@3^>8
LM+T
U
5 !
DÞ7
*(,& Y^G@3^>8
4Ð?MIMZ
@A
!
èDÞ}n?.3hÔiè9.
E
!
¢\7
*(,& Y^G@3^>8
4ÐçFQE?ùýó
,
ç
)Ð?ýI
!$16
#
-,<-
?%
"# P!
hÔi=
>>196_&
¢îqr¥=Ó9
%
óÿÒ
_ýÖÙÖhA
&
ý4¡ýI174Ð
MI<³@A
!
7 `4ÐMIê
"
"
!#&
"
!5
-.7
*(,& Y^G@3^>8
4Ð?çF
CJF4!5SH/H/WJOJHSJERNODR VSRJTD3DEHH3DGH
55
z¨¬:
*(,& Y^G@3^>8
4Ð-³
6MI
!
¯N¥®¯
%
Õ®¯n5ºq¯
&
óÿ
Ò_ý°0{
%
ý4?4ЯN
8-_
$
¢òï¤-.P08
"
8#!
£ã¥4ÐÍÎMI
!
®¯4Ð-5
!
¯4Ð
.[
!
4ÐÔ·
!
4ÐÔÅY
!
>.[ç-.
P0?8
"
"´%
?!*9#&
# 185!
µP1/|VWÕ
&T9
LM+TU
5
Þ
m
MG
·¸TU7
NT/1ZA-],Z[M
4V±]@AB
:-7RMGA&,<>&2&5($-2$>-)5#.&"%>#NT/1ZA-],Z[M =)0#,0(""#,#)%%,#-%;#)%
+3DGH
HJ
B3NFO/EODEH3GHJ/Er"
#
-,<-
?%
#
óÿÒ_ý
-G
,
ç)Ð
@DHG^OS2D3
,0GHPJ/E
=Ó9
,\GRJ3GOPHJE
ý4
KS0DED
$1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16
X
8 ? ? ? ? f ff f f f f ff fff ? ? ? ?
#! ? ? f ? f fff f f f f fff fff ? ? ? ?
!> f f ff f ff fff f f f f fff fff ? ? ? ?
"# ff ff fff ff fff fff ff ff ff ff ff ff ? ? f ?
>7
&T9
4Ð?MIMZ@A
!
èDÞ}
n?.3hÔiè9.E
!
¢\QE?ù
=Ó9
!
¡%
ý1=÷Z
%$$_
?hÔi
&
¢îqr¥ýó
,
ç)Ð
%
ÙÖhAÖóÿÒ_ý
&
ý4{Ô74ÐMIM@A
!
è
é?.I<ôõu`?/0
$
7 `4Ð
MIê
"
"
8#&
z¨¬:
&T9
4Ð-6MI
!
Í
ÎMI4ЯN[¥®¯
!
6MI4Ð¥[¯
Ö¯
!
4ÐE2³
!
¯N½Ú
& !
DÞÖý
44ЯN(M®8
"
7#!
Eºq¤
¥4ÐÍÎMI
!
4ÐÔ·
!
4ÐÔÅY
!
>
.[ç-.P0?8
&
3=Ó9hÔi
mý
!
þ6«&¨¬-÷4Ð¥¡
!
¥4Ð>
$
ÙÖhA
$1#!$16
#
-,<-
?%
¡
8 P
6ï¤Eoú
"
"´%
?%$*%8#&
#175
õö12/LM+¶ùXpq
5
¡+
«xK7+«ñ
&g&&
!p
BNEOGE
[RÊü
!
7Þ>Ö4Ð{¼Z[RÊü
!
F
"%
>&
7>%
5!
!
# µ
5
=ç
ñDÞ7
8
^a4Ðà?çFiwÖqz
"
85
-.7
&T9
4Ð?çF
CJF485SH/H/WJOJHSJERNODR VSRJTD3DEHH3DGH
YG
·¸TU7
1"4V±]@AB
:-7RYGA&,<>&2&5($-2$>-)5#.&"%>#1"\ =)0#,0(""#,#)%%,#-%;#)%
+3DGH
HJ
B3NFO/EODEH3GHJ/Er"
#
-,<-
?%
#
óÿÒ_ý
-G
,
ç)Ð
@DHG^OS2D3
,0GHPJ/E
=Ó9
,\GRJ3GOPHJE
ý4
KS0DED
$1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16 $1% $1# $16
X
8 ff ff ff ff fff fff ff fff fff fff fff fff ff ff ff ?
#! ff ff ff ff fff fff ff fff fff fff fff fff f ff ff ?
!> ff ff ff ff fff fff ff fff fff fff fff fff f f f ?
"# ff ff fff ff fff fff ff fff fff fff fff fff ? ? f ?
m
UG
·¸Tàb7X@ ¡¢
!
:-7RUGA=2%(<2#$&;<-,(.&).&)%>#2#3#2
&""&=,<#.%($(0#.-)0L@2#)#
Þ>
B3NF
hÔi
CGHG0JHS3GHD"_#
ý4
KS0DED !17 q#48G
óÿÒ_ý
-G
,0GHPJ/E 6#1! q#48O
ýó
,
ç)Ð
@DHG^OS2D3
=Ó9
,\GRJ3GOPHJE 7%1$ q#48R
55
! $
h$1$8&
1.
& +PDQG
[G
·¸4V@ ¡¢
:-7R[GA=2%(<2#$&;<-,(.&).&)%>#2#3#2
&"0(""#,#)%$#22()#.
4Ðà
(EQDOHOD00JED CGHG0JHS3GHD"_#
7r67 %71# q#48G
*(c^&GgD^! %>16 q#48G
&-# #"1> q#48V
*(,& Y^G@3^>8 6$1> q#48V
&T9 8918 q#48O
55
ÄÒ7-.Þ>¤9Ö¢y7 ?hÔ
i[RÊü(¤
!
óÿÒ_ý
%
ÙÖhA
%
ýó
,
ç)
ÐÖ=Ó9yý49*+
&
©4ÐhÔ
i`CK!#
!
=Ó97
8
4ÐçFþQ
!
ýó
,
ç)ÐÖÙÖhA¢î
!
yóÿÒ_ý9
*+
!
Úý47
8
4Ð?çF-_
!
7
8
^a4ÐçFþQ?ù=Ó9
!
¢îùý
ó
,
ç)Ð
%
ÙÖhAÖóÿÒ_ý
& 8
^a4Ð
àhÔi[RÊü~Þ>
&T9
?4
ÐÔJiy¢£4Ð*+
!
¢îù
&-#%
*(,& Y^G@3^>8
y
7r67%*(c^&GgD^!
9*+
$
_¡.Þ>Â.Ö1
!
&T9
4Ð?;^Q¥ST
!
¢îù
*(,& Y^G@3^>8%
&-#%*(c^&GgD^!
Ö
7 6^7&
HG
£¤
&lm~
!!
ñDÞ7íj
?^a4Ð<-.P0?çFÆñ
!
íj^a4
Ð7DÞ?ST;yDÞ?Æñ=³h
!
^a4
">%
& ( )
!"
"
5
Ð7Æñk1üE?aõ;DÞüST
$
Ú¡.³
Þ>.³°01
!
-.4Ðà?;^-.
!
ST
;*+_
$
lm_^a4ÐàñDÞ?
çFiwÖlmù5¼?
&
&lm(¤.^a4Ðà7-.?DÞ¤
?öù<*+?
!
yÞ>7^a4Ðà?ç
FÖÆñ=Â/
"
¹Eç
!#$$8#&
&«ñ?
!
DÞ7^a?Æñ=-.
!
=Ó95wAÆ
ñ^a?¼/àá
%
p1`
%
ØÞú
%
ÔqÕà
á
%
uç
"
PqÑç
!#$$"#!
ó7
#$$
[^aû
<×.
%
Ø
%
MI(¹#çÆñ
"
XKç
!
#$$>V#$
ýó
,
ç)Ð3
%1#_
?óÿ_ýn
>1>_
ç[0`Þ
!
£ãû<6ºnæçÆñ
!
NÆñ
>
!
ºañ0f
"
T¥!ç
!#$$8#$
ÙÖhA³û
<¼/ç;?<=Aºa>
!
û<6ºnæçÆ
ñ
!
ºaõa
"
ØÙç
!#$$"#$
óÿÒ_ý¥¼/ç
>
!
£ã¥6ºÆñ
!
ºaõa
%
Æñf
%
Hþ#I
!
û<ºa
%
º GR:;
"
VCç
!#$$>#&
&
+
8
4Ðà7=Ó9?;^Q
!
¢îù
ýó
,
ç)Ð
%
ÙÖhA
%
óÿÒ_ý
&
+?
_«ñíji?yÞ>?Æñ_¥¡mE
?Â/;
!8
4Ð7=Ó9MýhÔi?_
íji?7ó@A4Ð()óF?çº;
>û<üý?S;
!
Ú7¼/ç?ºa>
!
3¡4Ðà\S-÷ÆWSÚì¢74Ð?ç
FÂ7:jP
"
CÙZç
!#$$$#!
?Y&+
\ÙÖhAnóÿÒ_ý74ÐhÔiü
$
Ðh
ùwA!Ý^a¼/àá?4Ðà
!
5ó©7¼
/ç>?Þ>ü¥ST
&
¡6ú?³""
ØèÓ
ç
!%99"G$ %997$
¯µç
!%997 #!
ý4¡
%_
!_
?1ü¢£<=>
!
-|
%
¥ý
%
I
%
ýVÏç7^a4Ð?çF>
!
þ6&+«
ñçFü>?ý4Æ¥<=>7
!
+
~ý47
8
^a4ÐçFþ-_
!
5ó
ù3¡&lm\¥ZyDÞ}GH³
h
!
ý4}¥
$1$%_
$1$6_&
ü?}
ì:ý4çFþ-_
&
þ6¡
ñ^a
4Ðà{¼Þ>?çFçi
!
û7-.Þ>¤
ÄQ?4Ðà/Rã
&
¡Eºqlm³t!
{¼DÞ<=>ç
Fçi?4Ð[¥ÖÏ®?6ê÷Í
&T9%
9Â÷
Í
cJ^8%
¯Ì4Ð
%
¯Wa4Ðç
&
&¾«ñZ
ÖÏ®4Ðà
&T9
Ö
*(,& Y^G@3^>8%
GÏ®4Ðà
&-#%*(c^&GgD^!
Ö
7 6^7
ç
8
4Ðà{¼lm
!
$
&T9
FçFçi?³"6ý
!
ÜgF¢£
!
4ÐàñçFçi?³"
&
¡&+!
¡
op³h?¤1
&T9
û<ü?;^
!
¢î
ù
*(,& Y^G@3^>8%&-#%*(c^&GgD^!
Ö
7 6^7!
+«
ñ?
!
DÞ\óÿÒ_ý
%
ÙÖhA
%
=Ó9
aõ;ºa>
$
?_ÖÏ®4ÐüGÏ®4Ю
ñçFçi
!
Ú
&T9
¤ï?ýST;
?_Þn?OP4Ðàü¢£4ÐàS
&
ñ^a4Ð{¼ºa>?çFçiÖÆñ=
lmÆ¥³È?çi8ÓÂ7Þá?Mi
w!?û
fÚ
%
/[çÌS
!
Üó¡4
Ð`C
%
q@`CKlm^aÝçy£?Â2/
à
!
¥ºa>?Æñ=Ö;?lm÷?
jà
&
Ð34Ð?¤6ÖÞ>?Æñ=?-
.
!
¢<5óy1?Miw<³w*½
&
þ6
!
ñíjiwy^a:jiwÂÄ
Q?Þ>¤n4Ð7íjçFçi?þ
ó÷¢ò¸?þ
&
L M + ,
PqÑ
!
µVÇ
!
xÑ`
!
ç
4#$$#4
^a4Сºa>lmK?^
ñ
4
¹ºDÞ
!#!"!# #> ?6$4
PqÑ
!
µVÇ
!
íùÃ
!
ç
4#$$"4
=ÓºaÆñ=
4
"G&
!66
"!# %% ?%84
VC
!
Á)ç
!
x
5
ã
!
ç
4#$$>4#48_
ýþóÿÒ_ý
Zg
Ù¹
²xQ(·¸a?íÞþ+
4
DÞ
!!""8# 6"8 ?6""4
¹E
!
ß&
!
UX¬
4#$$84
ñ
Y++
iwºa>7¯Ì4Ð
?çF
4
DÞ))³
!""%# !8 ?!>4
C!Ã
!
Ù
5
[
!
5
Ê
!
ç
4#$$!4
^a4ÐOP{e
4
&()l
m
!%""%# %%7 ?%#!4
T¥!
!
pyò
!
Ð
5
Û
!
ç
4#$$84!_
¾aÜ
,
ýó)>Ø?l
my,ÔçFiw
4
DÞ
!!!"%%# 8%! ?8%84
¯
5
µ
!
ØèÓ
!
Яú
!
ç
4%9974
ñ¸èa4ÐçiQ<=
>n<=ADÞ?çF
4
"G&)³
! #6"%# "9 ?>64
µËµ
!
UJÃ
!
æ
5
M
4#$$74
^a4ÐÖ¢^ñ{e
4
{|
O)F)³
! #>"6# #$ ?#! 4
C-Z
!
¯
5
µ
!
KÏ
!
ç
4#$$$4
Â^a4Ðà7ç[0DÞ?
ST;lm
4
Mµpij
!8 6$ ?6#4
XK
!
`ÕE
!
V|
!
ç
4#$$>G4
"Ýú.g?Â÷Í4
Ð#J
4
^a)³
!8%"!# !!9 ?!864
XK
!
`ÕE
!
ø!
ç
4#$$>V4
=Ó97
&-?%
?4Ð#J.
gÆñ
4
^a)³
!8%"7# 7%> ?7#"4
Ø
5
Ù
!
½Ñ?
!
µHC
!
ç
4#$$"4
ÙÖhA7
4
DÞ))³
! 9 " 6 # #76
?#7>4
ØèÓ
!
Ä
5
ã
!
KÏ
4
ç
4%99"G4
DÞMwÈ?lm$
Q<=>7\X¯Wa
"B&+.$(/.1%A.,&%#
4ÐMI?@
A
4
K\²kE))³
°±()´
!6%"%# 9# ?984
ØèÓ
!
¯
5
µ
!
Ä
5
ã
!
ç
4%99"V4
DÞMiwÈ?lm%
ºa>4ÐMijà??VðÖ®{
4
K\²kE))³
°
±()´
!6%"!# !87 ?!8>4
ØèÓ
!
xÑè
!
ZÝ¥
!
ç
4%9974
ñ
Y++
iwºa>74Ð
?çF
4
"G&)³
!#6"!# 6!6 ?6!>4
BGQi g! &PGJ] , g! kG
>>%
5!
!
# µ
5
=ç
ñDÞ7
8
^a4Ðà?çFiwÖqz
i3GOD+B4%97#4)QHGV0JQP
YG3G3/QOP X!
nYo
4%99#4
^a4Ðà?(e
Iªb
4
{|
E))³
!"!# %%8 ?%#$4
-SEE B)4#$$%4*/UD0HDOPEJoNDQH/DQHGV0JQP EDLJEQDOHOD00JEDQ4(E
.JH3/D0BDU@J/0^,EJ
JEQDOHJOJRDQ/E ON0HN3DQ/TJEQDOHOD0Q4)EH/0)W2 ,220! " %6 #
6#" ?66% 4
IGPJ/NJR (!-GNFJD3!@G0
&G0DP\GRDP ,! kGVVG3,! kDEEDEQ-! &(1+4 #$$#4+PD DTDOHQ/T
2PSH/OPD
&HJ2GE/UJOIB! )0JQQG0RDYc! ,0H
ZGHD3P/NQDB C4 %9784&/
M/QPJRGY4%9"94(EPJVJH/3SDTDOHQ/T2DQHJOJRDQ/E F3/LHP GER 3DQ2J3GHJ/E
/TON0HN3DR OD0Q4gDQHJOJRDQ@J/OPD
"´?_
)W20GEGHJ/E /T20GHD
8
4Ðà¡Þ>1hÔiQý?4ЯN
&
% ?7
4Ðà¥
&-#& %4X$ #4
óÿÒ_ý
$16
#
-,<-
?%
!!> P$ 64
ýó
,
ç)Ð
$1#
#
-,<-
?%
!"# P$ !4
ÙÖhA
$16
#
-,<-
?%
!!> P$ 84
=Ó
9
$16
#
-,<-
?%
!"# P$ 74
ý4
$16
#
-,<-
?%
!#! P&
" ?%#
4Ðà¥
7r67& "4X$ >4
óÿÒ_ý
$16
#
-,<-
?%
!#! P$ 94
ýó
,
ç)Ð
$16
#
-,<-
?%
!!> P$ %$4
ÙÖhA
$16
#
-,<-
?%
!8 P$ %%4
=
Ó9
$16
#
-,<-
?%
!8 P$ %#4
ý4
$16
#
-,<-
?%
!8 P4
%6 ?%>
4Ðà¥
*(c^&GgD^!& %64X$ %!4
óÿÒ_ý
$16
#
-,<-
?%
!#! P$ %84
ýó
,
ç)Ð
$16
#
-,<-
?%
!!> P$ %74
ÙÖhA
$16
#
-,<-
?%
!
"# P$ %"4
=Ó9
$16
#
-,<-
?%
!8 P$ %>4
ý4
$1#
#
-,<-
?%
!#! P$
%9 ?#!
4Ðà¥
*(,& Y^G@3^>8& %94X$ #$4
óÿÒ_ý
$16
#
-,<-
?%
!"# P$ #%4
ýó
,
ç)Ð
$16
#
-,<-
?%
!"# P$ ##4
ÙÖhA
$16
#
-,
<-
?%
!"# P$ #64
=Ó9
$16
#
-,<-
?%
!#! P$ #!4
ý4
$16
#
-,<-
?%
!"# P&
#8 ?6$
4Ðà¥
&T9& #84X$ #74
óÿÒ_ý
$16
#
-,<-
?%
!"# P$ #"4
ýó
,
ç)Ð
$16
#
-,<-
?%
!!> P$ #>4
ÙÖhA
$1#
#
-,<-
?%
!#! P$
#94
=Ó9
$16
#
-,<-
?%
!"# P$ 6$4
ý4
$1#
#
-,<-
?%
!!> P
Y32P/0/FJOG0OPGEFDQ/THPD8 OD0Q0JEDQGHHPDPJFPDQHRDGHP 3GHD/TRJTD3DEHH3DGH
-,<-
?%
!!> P$ 64@DHG^OS2D3
-,<-
?%
!"# P$ !4
,0GHPJ/E $16
#
-,<-
?%
!!> P$ 84,\GRJ3GOPHJE $16
#
-,<-
?%
!"# P$ 74KS0DED$16
#
-,<-
?%
!#! P4
" ?%# +PDOD00JEDJQ7r674"4X$ >4-G
-,<-
?%
!#! P$ 94@DHG^OS2D3
-,<-
?%
!!> P$
%$4,0GHPJ/E $16
#
-,<-
?%
!8 P$ %%4,\GRJ3GOPHJE $16
#
-,<-
?%
!8 P$ %#4KS0DED$16
#
-,<-
?%
!8 P4
%6 ?%> +PDOD00JEDJQ*(c^&GgD^!4%64X$ %!4-G
-,<-
?%
!#! P$ %84@DHG^OS2D3
-,<-
?%
!
!> P$ %74,0GHPJ/E $16
#
-,<-
?%
!"# P$ %"4,\GRJ3GOPHJE $16
#
-,<-
?%
!8 P$ %>4KS0DED$1#
#
-,<-
?%
!#! P4
%9 ?#! +PDOD00JEDJQ*(,& Y^G@3^>84%94X$ #$4-G
-,<-
?%
!"# P$ #%4@DHG^OS2D3
-,
<-
?%
!"# P$ ##4,0GHPJ/E $16
#
-,<-
?%
!"# P$ #64,\GRJ3GOPHJE $16
#
-,<-
?%
!#! P$ #!4KS0DED$16
#
-,<-
?%
!"# P4
#8 ?6$ +PDOD00JEDJQ&T94#84X$ #74-G
-,<-
?%
!"# P$ #"4@DHG^OS2D3
-,<-
?%
!!> P$
#>4,0GHPJ/E $1#
#
-,<-
?%
!#! P$ #94,\GRJ3GOPHJE $16
#
-,<-
?%
!"# P$ 6$4KS0DED$1#
#
-,<-
?%
!!> P
!
!"#$
5
ØÙÚ
"
9>%