免费文献传递   相关文献

Progresses in screening active compounds from herbal medicine by affinity chromatography

亲和色谱应用于天然活性成分筛选的研究进展



全 文 :)$5
s
4
t ñ
&$
òñ
#
w
X-SF&$$ ;-+# 9TU,R$ )$5
̥ͷƒºÏЍŽÑÒ¤ˆ‰Š‹
jkl

!
mnn
)
!
>of
)
!
pqr
!)
!
F
0Œ“ Ž
!
q! rq
)$$$(% )F
q! Ž
!
q! Ïq
))$4#

uv
#!
Ì¥ÍÎÉ
!T[P0PL6,RU-.TL-ZUTER6
ó[Oåƒî}ö¤#’%Ž3° ¤ÍΘÉ
(
åƒ_’“¥î}ö
¬­Dì¤wO%ÁŽÌ¥ý
$
ÔZK_’“¦²¶YÌ¥Ž¤_’“$°:3
(
1˜É!»OŠhÍΐ°¥Ž
ÑÒ
$
‚6[O¦@¶ÑҘÉþ5‡ƒºrOŽ,“¤ÑÒ
(
1^€˜´Ì¥ÍΤg‹ûü
%
ÑÒ()nV„Œ¯
ÏЍŽÑÒ$¤‡ƒŠh.aË
(
igŒ‡ƒ™>ŠhM1
$
Ÿwã/FgŸÌ¥Íί,“ÑÒ$¤‡ƒ
(

wxy
#!
Ì¥ÍÎ
)
ÑÒ
)
ÏÐ,“
)
…†YÍÎ
)
¢½ÍÎ

z{)(
#!)$&33$

\|}P
#!
ŒS½«“³U”¾
4$(%4#%%#%
ͲЎˆ³U”¾
)$4))%$$)#%
q!Œ
&
ÑÂÒib,

”¾
)$3QQ$)#

~A€
#!
!
pqr
!
ÍÓ
!
Ž•–
!
™šºd¤­Ô՟Ö
!BOS$4(5)%#(! M3.TPS$6/01W/DFOVWF,0

A€‚
#!
jkl
!
Z™š
! BOS$)#(5&)%! M3.TPS$[6D$51)#F,-.
A32O37::7:.4:H3774.4O -H1.J7H2,;2>40:832,673<-/
,70.H.47<@ -8.4.1@ H632,-12O3-;6@
GM;@QP0Z3DRW

$ B^;@8RT03DRT0
)
$ aIaP3.P0Z
)
$ QIHPT0Z30T0
$)
!
!FP)?%+$0)&$,9.(%+0%)/$%-@&%-6##$ !(&% .(%+0%)/$%-F&C)+#$6$ :%&H&3 )$$$($ !(&%)
)F!,-)3),9.(%+0%6$ 2%&3#/ F&C)+#$6$ T()&H%&3 ))$4$ !(&%
*B<:13-H1+!2[P0PL6,RU-.TL-ZUTER6PDT,RU-.TL-ZUTERP,.OLR-V [-UDOETUTLP0Z.-SO,WSODWDP0ZLRO_P0VP0Z,RTUT,LOUPDLP,D-[LRODLT3
LP-0TU6ERTDO*PLR E-LO0LPTSVUWZ.-SO,WSODFBRPD.OLR-V ,T0 _OEOU[-U.OV TDTRPZR LRU-WZREWLD,UOO0P0Z.OLR-V T0V T,RU-.TL-3
ZUTERP,DOETUTLP-0 .OLR-V L-D,UOO0 TeTUPOL6-[T,LPeOVUWZDFBRPDETEOUDW..TUP\ODLRORPDL-U6-[T[P0PL6,RU-.TL-ZUTER6$ D,UOO0P0Z
LO,R0-S-Z6-[T[P0PL6,RU-.TL-ZUTER6$ T0V TEESP,TLP-0 -[T[P0PL6,RU-.TL-ZUTER6P0 D,UOO0P0Z_P-3T,LPeO,-.E-W0VDP0 ROU_TS.OVP3
,P0OD$ T0V LRO0 VPD,WDDODPLDTEESP,TLP-0 EU-DEO,LD$ P0 -UVOUL-_U-TVO0 TEESP,TLP-0D-[LROT[P0PL6,RU-.TL-ZUTER6P0 VUWZD,UOO0P0ZF
*a7@ T230:+!T[P0PL6,RU-.TL-ZUTER6) D,UOO0P0Z) ROU_TS.OVP,P0OD) ,OS.O._UT0O,RU-.TL-ZUTER6) SPEPV UT[LDLTLP-0TU6ERTDO
,RU-.TL-ZUTER6
02.#!&b%(cFHZH,,(&!#&&
!!
$,On]E
$
ÔÕý-
$
ABُóŒgŸ™š‚
ƒ¤“µ¹Ð
$
¦ÏÐ,“$|õŽ[6ó$,ˆ‰
¤ì€˜‹D[
(
ÐA
$
‡ƒWä¤ÏÐ,“°%-˜
É
$
˜ž´ŒŠh°
$
F#’,,ÙUVÑҌ$
%}¤Bُ¤˜ÉÑÒ$,Ž
$
9w/
$
Äú$
hö´KX
(
Ô_’“°c}) •¦@¶,“ÑÒ(
)ö#’
$
!Ÿ6+´ÏÐ,“¤%-‘Šh°i¯ù
ŽØ|
$
Ë4!Ÿ«ØL
$
%¦ÏÐ,“ŽÑÒ°5
$
»OJ¯[}²55˂ƒ–—
$
ŸG戉ZK¤L

(
Ì¥ÍÎÉ
!T[P0PL6,RU-.TL-ZUTER6
ó[Oåƒî}ö
¤#’%Ž3° ¤ÍΘÉ
*+
(
¯Ì¥ÍÎ$
$
Ô¾
•f¯,“
!
ÔÃ

%Á#’¤“µ
!
Ô¹

î}ºÍÎ\ì

$
—[ÍÎþ
$
·’“œ±ÍÎþO
$
¾•î}öàð%Á
#’¤“µÔ¯ÍÎþgðGHh6
$
¦A$ü·’“ì
ŸÌ¥Ž6¹Ð¤°
(
$,%-“!˜±°X™
$
6
+¯ö‡¤Ì¥ÍΉÑÒN‚
(
iÄ,“¯Ì¥Í
ÎUV¤¤GH%Ž
!
GHOì1ù¶¼ 

•,“¤
ŽEFö÷
(
L^€˜´Ì¥ÍΤg‹ûü
%
ÑÒ()
nV„Œ¯ÏЍŽÑÒ$¤‡ƒŠh.aË
(
!Q
Ì¥ÍΤg‹ûü
Ì¥ÍΤg‹œû.Ñs¤ûü
*)+
$
üY6[g
.)4$.
¾Gn&
#
̥ͷƒºÏЍŽÑÒ¤ˆ‰Š‹
K6ê¤()
$
þ5‡ƒºÏÐ𓍎“µ¤°¥*
_
$
Ÿ„ÑÒ¥c}
(

($
s
$
Ö%,~
8LTUKO03
DLOP0
Ô¿`.”ꮯ¦¼å
$
ˆ‰.”Ã¥”Û¤ö
›‚ƒ
$
6Ì¥ÍΤÀI
( ()&
s
$
ÁÈäá
M0ZOSRTUVL
%:.
&
î}_ÔÃہ
$
‚6°ð“Ž“µ¤˜É
$
6Ì¥Íΐ°˜É¤îL
(
š·¤
#$

$
Mzök^
ƒÌ¥ÍÎ()
$
°*_Iü.
%
”Ã&
$
¯•wì
$
°±
`
%
ê@`ê}
%
©¢`
%
QwB}¢&¹ÃC쟄rOÔ
¹¤î}_˜É¤:ü
$
Ì¥ÍÎ()d°g‹
( (#
s
$
ô%,~
¥
YPS,ROK
3‹.Ì¥Ô(ä

$
Ç.
%
”Û
%
”Ã
%
‚`
%
±ð`
%
e>ê8`
%
``
ø
%
Y`ø
%
æŒ
%
…†&
$
PÛð“%ÙÌ¥ÍΘÉ
(
(%$
s
$%:.
&
ëìì.Â

ʽ¥˜É
$
½
go.Ô(äÛÃ!+HŽpâ
( (%)
s
$
Ö%á
YWS[
%: c®ÍΘÉ
$
Š[X3‹.Ì¥ÍΤ‡
ƒ
$
^1Ì¥ÍÎ7ƒº,“Ñ҈‰
(
š·¤
4$

$
0ÈÍΘÉ
$
žìÔ(ÍΘÉ
$
ULjÍΘÉ
$
}(
øyÀ Ì¥ÍΘÉ
%
’Ô’“ÍΘÉök%:
(
(%
s¦}á
R^SD-0
%:Ÿ²¸ïà~}‚6|ä¦
ٜöÌ¥ÍΘÉ
$
^1Ì¥ÍΤg‹Ä˜.[gi¤
OP
(
Ë÷ºÌ¥ÍÎ()¤g‹ÈÐiÃ6+ƒºÏ
Ð,“¤ÑÒ
$
KóŒ´üP,“ÑÒ()¤ïÛ
%
g‹¥
‡ƒÞ}.¢ì€¤1¹Ð•()‰Å
(
œ±1¢sÌ¥ÍÎö÷()¤g‹
$
šO
]?C<
ÍÎ
þ—[()Ÿ„rO¯ùƒ()¤þ5‡ƒ
$
Ÿ„ãEÌ
¥Ô¹¤¹Ðˆ‰¤j˜
$
2¢Es3!X=ð:.]E¹
ºË»Ô¹¤Ì¥ÍÎ()
$
i¯ÏÐ,“¤ÑÒxygŸ
.G3G쀤‚ƒ
(
îÀÔ¹¤On¥ÑÒUV¤Ë»
$
®ƒ¤Ì¥ÍÎÑÒ()Ç
#
ŸHÃ
%
.
%
`ø1
A;2
6
Ô¹¤Ì¥ÍÎÑÒ()
%
…†YÍÎÑÒ()
%
¢½ÍÎ
ÑÒ()
%
 c®()&
(
rOÌ¥ÍÎ()¯,“Ñ
Ò
%
U:ïÛ
%
°–—&˜­¤%Íˁö»
$
Œ¯ÏÐ,
“gü¥c}&xy¤‡ƒË¾…‹
$
6ÏЍŽ¤g
ü•…†,“7g%8.óÿðϤÑÒ()SÚ
(
(Q
Ì¥ÍÎÉÑÒ()
Ì¥ÍÎÉÔ¾•f¯,“
!
ÔÃ

%Á#’¤“µ
!
Ô¹

î}ºÍÎ\ì—[ÍÎþ
$
·’“îÀÍÎGH
h6¤Ë»A$ü°
(
»O
$
Ì¥ÍŘe
$98$;9>
&EOØ|ôƒ
$
$ü¯ùÑÒic}$,Ž
(
š
OMz´Ì¥ÍΖ«¤ujŸ„‡ƒ¤ýþ
$
EOÔ¹¤
Ì¥ÍΟ„Ë»nV¤Ì¥ÍÎUVÆyWMz‡ƒº
$,Ž¤ÑÒ
(
(X!Q
HÃ6Ì¥Ô¹¤ÍÎÑÒ
!
2s3
$
šO,“‚ƒ
wÖ¤!X|â
$
ŸHÃ6ZKÑÒ$,$¤Ž6$
,ÑÒ¤¹LÅN
(
!Ü&
*4+
¯
)$
c{
$
sP
$
Ÿ

g
HÃ6vK
$
ÑÒ.
5$
O®ƒ$,¤
&$$
”O%-“
$
1
Y.
5 $$$
”O𓍎|}#0
(
6.g$Aƒ,¤–—
%8.[N$VÜÀ
(
ÐA
$
WäÑҘÉ4îÀ·’“W
¾‚ƒ#0
$
YÉP}ÿƒ“µ
$
ÄN‚¶)²
$
lmM
ý“ý!Ä
(
ÔHÂ6Ì¥ÍΤî}ö
$
ïÛÌ¥ÍÎ
ÑÒUV
$
ÏÐ,“%-“$¾•HÃgð%Á#’¤
¯ÍÎþ$gðGH
$
•YÍÎGHh6¤“µ°73
$
¦A$üŽÑÒ¥Íΐ°»OŠh
$

%
BÙ¤gü
ÏÐ,“$¤Ž“µ
(
Z™ƒºÏÐ,“ÑÒ¤HÃ6
Ô¹¤Ì¥ÍÎUVBԓ`HÃÌ¥ÍÎUV
$
Ç4H
ÃÌ¥ÍÎUV&
(
ôºHôÔÃÒLŽ«¬‚ƒK²
$
ŸHÃ6Ô¹¤
Ì¥ÍίÏÐ,“ŽÑÒ$ÿBK²¤ÒLŽÄ
‚ƒ–—þP
( YT0Z
&
*&+
ÔÈì‘
)
3
ԓ`HÃ
!

)
3
2>
@±0ÈPî}¯²¸~}¬­
$
—
)
32>
Ì¥ÍÎ
þ
$
^ƒÌ¥ÍΘɕ{ódhOìµÎ
!d3B^G398

ƒ
$
¦$,—t}~%-“$ÑÒ:BُVŒÜ
$
ɹ€ûmÍ`
2!]8Q2
¥Ê’ô
(
%-“$ÿBŠt
‚ƒ¤
)
32>
u”¾•î}ö$¤
)
32>
gð%ÁŽ
#’AàðÍÎGH
$
•
d3B^G398
ƒ
$
$üŽ_’“
¤¯ù°¥c}
(
ÐA
$
Hä—[„î}_NYK6ý-
$
Hä`ø
µ%Ž¤†.Ì¥ÍÎ^ƒËúKô
(
¯HÃî}_±²
$
$
HÃ`øÌ6ˉq+¤†ÔÕî}ö–H¹«g
ðÃ%ÁŽ#’A¤†ŒGH%ŽgðÀ_
(
’.³&
*5+
ƒÑ>Üw»´~}¬­–H¤;͇¤ÍÞ¹ŠhEÎ
AB§Ã%ÁŽª®
$
i¯³¾ö$u˜
BUPD$ MAB2
¥
;T&U
$
ƒºB§ÔÕî}ö–H>¹¥~ɹ
Dì¤4U‚ƒ
(
ŒFË4¾Ÿ²²5FGŠH䍎
¥ÒLŽ
$
Öa:.î}ö¬­Ã%ÁŽ½¾«¤·¸
(
—[¤ÍÎþ!^ƒ

9¤Oì
(
’Q¤î}_Hägüo}OÌ¥ÍÎ,“ÑÒU
V¤‡ƒ
( M&
*#+
ˆ‰.î}_ #V±Ù_“.Ã
+s“‚HÃ
!??2>
#

¤ÍÎ%Ž
(
$VÔ
??2>
#Ÿ0
ÈPî}¯>A¹cÙ_~à ¬­
$
‚6ÍÎî}ö
$
»
O
$
Ô
??2>
##’¯&…þ¬­ïÛ
??2>
#&…Ì¥
Íψ‰Ë»î}_>ÏΤ̥ÍÎ%Ž
$
ŸYöÔÃ
Væî}_·¤
??2>
#Ì¥ÍΤ#’%Ž
(
#0¬þ
$
ïÛ¤
)
OÌ¥ÍÎUVNÿBÌ/¤ÔÃGHŽ
(
??2>
#¯ ¢A…†
$
¢P
$
¥)*…†ÌO쀤ð“
‚ƒ
$
•
)
V`–æ
$
t¢Á®
$
¾NQFR_¥Ståæ
B6+¤÷ã
$
ˆ‰Œî}_·¤ÍÎGH%Ž
$
6Œƒº
ÏÐ,“ÑÒÞ}¹Ð
(
•e
$
Ì¥ÍÎJ!ƒºÌ¥Ô¹
¤|õ
(
MHóô
>Z

óWä$,MH¤€BُD
[
$
,Žþ5
$
ÿBþ5¤Ë†
%
”ÏÊ
%
+²¨©
%
â
œGU&,Ž
$
K‚ƒ–—q;BÙ5þ
(
›‚&
*%+
@
±ÔHóô
>Z

•Mٍ_©¢`ê}
#J!OE-76T,LPeTL3
.44$.
)$5
s
4
t ñ
&$
òñ
#
w
X-SF&$$ ;-+# 9TU,R$ )$5
OV8O3ERTU-DOB9#J$ M28#J
ˆ
$
—[ŸMHóô
>Z


¹¤Ì¥­µ
$
ÑÒ1Y

g
>Z

¤#’`ø
$
6—[n«
#î¤ÏÐ_’“¤Ì¥Íέµ%8H9ÜÀ
(
J6Œ
KrOn$,¤ÑÒ%8ÅN
(
(X(Q
.6Ì¥Ô¹¤ÍÎÑÒ
!
.
!O0\6.O
óð“Ãi½
Pß±²¤‘_
$
H•rnÃ8͇¤gð
(
.¤‘_Ù
hó¦
$
iÿB¦5¤ä[Ž
(
|õw‹.¤‚—1‚¾
6,“ÑÒ¤[gi¤˜‹
(
î}_.()¤:ü•
g‹go..´M[U
$
YÉìýåƒ&pâ
$
^.ļ
ÑÒ$,Ž6!¾
(
î}_.()^.@±ª®
%
0ÈP#’
%

%
z&˜É}(º|ä[}ëì
$
ÐG
Š.îB¤‘_Ž
$
Ö!ÑyFìý^ƒ
(
Ÿî}_.6
()¹Ð¤Ì¥ÍÎWþ5ƒºrO.‚—¤ÑÒ
$
M
#
!
3
`ô.
*3(+
%
Ñ>Ü.
*$+
%
¥`ø.
*+
%
Ò4».
*)+
%
t
€<`‡_.
*4+
&
$
6rOæUVM`–æ
%
pUæ
%

£
%
¦t¹Ÿ„✪hŽåæ&%8™šÜÀ
(
šO.•
åæ÷ã¤j˜ˆ‰
$
Ÿ.6Ô¹¤Ì¥ÍÎÔ¯,“gü
$ÌY㲤‚ƒ
(
Ôî}_.()•ÍÎ()Ÿ„
98
ƒ
$
¯ÑÒÏÐ
,“Ž˜­BOþ5¤‡ƒ
(
mn&
*4+
Ô
2î}
¯Ó@`ïd|Ã
$
—[
2Ì¥ÍÎþ
(
#’¦Ùœ
ö]°ÑÒý-Ãã$¤
2‚—
(
‡ƒÝÔYå&
5
OY4¤
2´ÑÒUVŠhVæ
$
Íe˜ÉÿB¦5
ÒLŽ
(
ԕUV‡ƒº$,Fs„¢nÑÒ
$
1Y
5
gÿ
B‚—
2.Ž¤Bُ
$
ÄÿBìüŽ
( QW0[T0Z
CP
*+
&Ô!
3
Iü.̯fŽTÂà ¬­
$
‚6ÍÎþî

$
ïÛÌ¥ÍÎãä
$
•
98
ƒ
$
¦ÏÐ,“²q(m
$ÑÒ!
3
Iü.‚—
(
ÑÒ:¤
4
OŒmbn_’“
$
Š
[X#’
IX$98
¥
;9>
ÎAP}.#î
(
Ô.‚6î}ö
$
•ÍÎ()ƒ
$
¯ÏÐ,“Ž
ÑҘ­ÿBö겤ðÏ
(
°.œî}_·G0O
ì²²+u
$
´Ü
%
4
%
ݟ„B–3¤ÎH+u
$
6Ë»
3gŽµŸ„%-˜:¤ÏÐ,“¤ÑÒ%8.!¾
$

.ÑÒ3ž
(
Ÿ.6Ô¹¤Ì¥ÍÎÑÒãäÿB‹U
$
¦
Ù
$
%ÁŽ²
$
!ìýåƒ&ðÖ
$
!Տ6ÏÐ,“¦@¶
ÑÒË!1Ťì€Nÿ
(
ÐA
$
Ÿ.6Ì¥Ô¹¤ÍÎÑ
Òãä0¯[}¤pâ
$
.¤î}_±²Ë\À.¤[J#
î
$
Ö!¾\À.¤ëì#î
$
A¤†.Ž¤1×D1

$
ØÑҖ[Bçj˜ˆ‰
(
(X)Q
tS`ø6Ì¥Ô¹¤ÍÎÑÒ
!
,“Š˜Ã8·
$
•tS`ø¤#’ó[g쀤±²
$
o}O,“¯Ã8¤
Ž¥ú©
(
tS`ø#’h
!ESTD.TEU-LOP0 _P0VP0Z$??J
Ñ»3gŽ
$
Ì¢Ž
$
Ü4Ž&¼`
$
·¸O,“¤ªz
%

ñ
%
Pߥ8s
!2A9M(
ûB°,“!Ù±…†Y
$
¯
Ã8ñAúÌ,“¤Í‡
(
šO°,“¯Ã8¤B§
$
`ø#’,“ÙÚ:°,“
$
‚6,“Ú0ô±Š°,
“‰5
$
e/,“‚ƒ¤ŠyOì
(
tS`ø#’+u.,
P¾ýDÏw
$
KyC—.,“¤‘_ñ
(
¼•
$
tS
`ø#’¤ˆ‰„Œ¯Ì¥ÍÎ$¤‡ƒ´ÏЍŽ
¤ÑÒÿBì€Äa
(
¹ºtS`ø#’¤Ì¥ÍÎ()¯$,Ž¤
ˆ‰$BKE¤‡ƒ
(
!?Û&
*&+
Ÿ²¸~}6¹µ
$
ƒ
ܹÍÞɒ.MtÞø`ø
!]82
ÍÎ\ì
$
ƒºÝÞ
ß$Ž¤ÑÒ
(
1$VÒL
E]
6
%F&
¤-Üø<=
œ6³¾ö
$
³°
$F .C..P0
N
$
¯ÝÞß$%-¤oð“
4
]82
ÍÎk$:ü
)
gþEGH
$
ôºÔÕ`ø¤#’
͇K]
$
Ag°KT
$
ìj?àÎ
(
Š[XŸÍöÍÎ
°
$
ƒ
98
Ø|ô
$
c}:.üwè¼ÙÒÿ4
%
Q_è
üÙÒÿ4
%
ÒÿÛ4
% #3I3
¼_¹Òÿd4
&
O
(
]82
Ì¥ÍÎãä[ô҃
E]
6
%F&
¤-Üø<=œ6³
¾ö
$
u˜b¶wŠ!Ÿ%¦³¾ö¤Hü¾ý
(
•,“#’¤tS`ø€6
]28$]82
‚6î}öþ
5‡ƒº,“
3
`øˆ‰$
(
A !

3
܎``ø
!2@?
•,
“¤#’JËù_I
$
%¬ó´º4Ž,“
$2@?
6€#
’`ø
*5+
( bTUP0OXWPZ0POU
&
*#+

]82
¥
2@?
Ì¥Í
Îþ
$
•
98
Ø|ôƒ
$
ˆ‰Ì¥Íδ,“`ø#’¾
ý
(
¼K$V1#0•^ÐeÞ^ƒS§43É&˜É
1#0¤ö÷Ž
$
#0¬þ
$

]82
þ1Y¤`ø#’
¾ý#0•^Фö÷ŽK¦
$
A
2@?
þö÷ŽKî
$
A
2@?
þ¤#0Öó
]82
¤Ó‘
( bTUP0OXWPZ0POU
[ïÛ.
¦@¶¤,“
3
`ø#’ÑҘÉ
$
vgFÑÒOì:º
4
.P0(
^ƒ[g³¾öŽ5QƒºBF¤3
$
`ø#
’hö«¤,“Ô¯ö»¤Oì Hü:3
$
Ÿ•Ô,“ä
Á•`ø#’²5¤²
%
$
%
în
(
(X%Q
Ÿ
A;2
6Ì¥Ô¹¤ÍÎÑÒ
!
DWp2|ÃüÙ
p`pÜ
!A;2
³—O…†¤#¾
$
¯ðú±²$Ì
Oî쀤‚ƒ
( A;2
óåE,“¤€‚ƒwÖ
$

 •
A;2
#’¤˜:€Ç
#
á₃
%
ãä#’
%
4U
#’&Ã0È#’
)
0È#’
)
/ý‘œ
)
廂ƒ&
*%+
(
Œ$
$
ãä#’¥á₃Ë\À
A;2
¤[J#î
$
ÄÿB
ÒLŽ
$
A6Mz÷äÝÖ
(
2s3Mz´,“Ž:
 •
A;2
ö›‚ƒU:g¤uj
$

A;2
6Ì¥Ô
¹ÑÒ,“%8.!¾
(
8W
&
*+
^ƒ:*æ“
A;2!,L3A;2$

A;2
 
[›¤-ܹ«•>A¹~}¤>¹?->P
$
’.
A;2
Ì¥ÍÎþî}ö
$
Ÿ˜eØ|ôØ|
$
ƒº°m
Ñ
%
mç¥9H$¤Ž
(
¯³¾ö¤ÒL
$
ôº
9Z
)g
!Ÿ¥
A;2
 ¤-ܹ#’¦AÌYT}
A;2
Œ
ߤ‚ƒ
$
•Ž,“è7
A;2
¤Ì¥(Ö
$
Ø
9Z
)g
¤
+uWX
A;2
Ì¥“µ¯ÍÎþ¤GH
(
wŠƒ¶¤+
uJ¾ÌYu]Hü¤‚ƒ
(
6.%¦ý-F¯
A;2
þ
¤°Ù0
$
^ƒ.!Õ+u
9Z
)g
¥wŠ‰5¤³¾ö
.&4$.
¾Gn&
#
̥ͷƒºÏЍŽÑÒ¤ˆ‰Š‹
´mÑ&%-“Šh.Ž5°
(
ÐA
$
ôºõø³¾ö¤

$
•UV͟¥µÎƒ
$8W
&ïÛÌ¥ÍÎ
=^A8
þ
c±ÍÎ
$
įñ[±©8§ø·Šh·y°
$
•µÎ
ƒ
$
$ü.ý-ÃãF¤¦Ù°
%
ÑÒ
%
Žc}[
Ã_±²
(
(X#Q
…†YÍÎÑÒ
!
üP,ˆ‰¬þ
$
,“ªzCœ
±…†Y¤3«1‡©
$
i•…†Y%ÁŽHÃ1.#’
AgŸ,Ù
(
¼•
$
_’“¤Ž•…†Y¤@4Ž¥,“
•…†Y¤Ì¥Ž6»ö÷
(
Ié=êº
((#
s%:.
…†YÍÎÉ
!,OS.O._UT0O,RU-.TL-ZUTER6$ <9<
¤Ê
½
$
Ô𓍎¤…†Yî}¯%}|쭂6î}ö
$
ƒœöÍΤ˜Éˆ‰,“•…†Y„YHäö›‚ƒ
$
¾¦UV,“¯Ã8¤‚ƒ±²
(
üP…†ð“gü
$
…
†Y0¯EOHÃ
$
ñg…†¤HÃ65!
$
4
m$
&
=
¶J
(
Ë»OnŸ„MÃË»1(¤…†Y0¯OË»
¤HÃ
%
° @Þ
%
.&هwÖ
$
^ƒË»1(¤…†Yƒ
ºË»,Ž¤,“ÑÒ
$
ãë2ÏÐ,“E
$
Ew
Ö¤‚ƒÊ½
(
…†YÍÎɂ6[Oi¤,“ÑÒNÿ
$
Wþ5ƒºÏÐ,“¤Ñ҄Œ•HÃÌ¥ý¤ˆ‰
(
´
º…†YÍÎÉ´º$,Ž¤ÑÒ
$
˜Yì&
*(+
¯
aË$o#.1O€¤…†YÍÎUV
#
t…†Y
%
S
¢…†Y
%
¥¦ …†Y
%
€…†Y
$
ŸÑҙšStå
æ
%
`–æ&,“¤Ž
(
2s3
$
…†Yî}öOn¤+E^1…†YÍΤÑ
ÒB.ãþ5¤‡ƒ
(
MŽÆž)*…†
<9<
UV
*)$+
$
M
í9Y…†Y
*)+
$
£…†Y
*))+
&¤:ü
$
^1ãE,
Ž¤,“1ŸÑÒ
(
<9<
UV!˜%-°X™A6+$ü¯ý-¤Ã
ã$ÑÒ:Ž
$

$

$

(
,“‚ƒwÖ]
E
$<9<
UVŸ²C5FGŠ.…†Y¤‰ÂŽ¥YHä
Ž
(
$üŸË»,Ž6vK
$
ÒLË»1(Ÿ„On
¤…†Y
$
ƒŸEwÖÑÒ
$
%¦ÑÒú$h
(
1˜ÉÿB
ú$h¦
%

%
ϔ
%
!Íýåƒ&ðÖ
(
ÐA
$<9<
UV
_0¯[NpâC€go
(
…†Y6ð“‘_
$
ö´º[ô
ÍÎ
$
YHÃ65K:
$
þÙKX
$
|F¶K:
$
Äð“Y¤
%ºŽµ¤†³¾ö6<=ø
$
•µÎãäËWÔA¤†¯
ùc}¤fÍ
(
6go•pâ
$
!ï³&
*)4+
#’þ»/(
)
$
òr.c±œöÍÎ
(
Ÿ¦¬
M@G>
…†YÍÎþ6
ñ[±
$
ŸÍ‹ÍÎþ6ñc±
$
•
98
Ø|ôƒ
$
ÑÒò
$¤Ž
(
¯ñ[±¤…†YÍÎ$
$
$,%-œ$
•…†Y%ÁŽ#’¤“µgðGH
$
i@±[îÍö
<

¶þŠh©8
$
©8‰·
$
»/Íñc±¤Í‹ÍÎþŠ
hc±°
$

98
Ø|ôŠh3
$
6+01Ž¤
#îp2
(
[
%
c±Íΐ¬Ÿl
%

3
l6³¾ö
$
¯G
æ†YÍ΍Ž¤»Oð³.•
98
Ø|ô¤WÔ
$
$ü¦
ِ°
%
ÑÒ
%
c}[Ã_
(
‡ƒ•c±ÍÎ()
$
VBá
½ïÛ
]OE@)
…†Y
%
í9ñ2…†Y
%2&4
…†YÍÎ
UV
$
¦Xç
%
9H
%
mD
%
€&’
%
Òÿ&ÏÐ,“$°:
.ӣ
%
ÖFðŽ¤Bُ
*)3)5+
(
ԅ†YÍÎþ•
͋þ#’
$
$üEOŽ_’“¤¯ù°c}
$
6…†
YÍίÏÐ,“ŽÑÒ$¤‡ƒ3‹.ÅN
(
…
†Y6𓍎
$
¯^ƒ±²$
$
…†Y`ø¤D¤
†…†YÍÎþGH¾ýÀJ
$
ìýŽ1ËYGæ
$
Ä^ƒ
ËúKX
(
6go•pâ
$aWT0 AP0Z
&
*)#+
9¿…†YÍÎ
þ¤—[±²
$
ð_.…†=¶
$
å»Oì
$
œ|³°&H
=
$
iu˜
&f?G2$
^1…†YÍÎþ¤ìüŽ¥^ƒËú
²|%¦
(
(XQ
¢½ÍÎÑÒ
!
¢½
!SPEPV UT[L
ó…†YŒ“#î8
õB%º¢µ¥%º`øµ¤ïJy
(
¢½¥…†¤åE
½¾
$
Mp<‡¤
%
`øµ¥¢n¤‡©&­ö÷
(
ˆ‰¬
þ
$
¢½´·¸£gð
%

%
•–¤p<‡¤@NŸ„®
¯p<@N&EO¼`NÿBª«‚ƒ
$
¼A62s3
£™šˆ‰$¤iÝÖ
*)%+
(
ö¼º…†YÍÎ
$
¢½ÍÎ
+².ÑÒ¤%ÁŽ
$
Ä^ƒËú²²e/
(
òóó&
*)+
î,“¤¢½ÍίùÑÒUV
!SPEPV UT[LDLTLP-0TU6ERTDO,RU-.TL-ZUTER6$C><(
Ô¦
I)5
…†$%-¤¢½î}º~}|Ã
$
—[
BUK2!
Ñ>Ü`
ø‚.HÃ

¢½ÍÎþ
$
ƒº$,Ž¤ÑÒ
(
©õ
BUK2
¤¢½ÍÎþÿBEF¤%ÁŽ
#
î}ö¾•ŸÑ>
܂.HÃ6wÖ¤,“%ÁŽ#’àðGH
( BUK23
¢½
ÍÎþG0Oì6

gt
$
^ƒËú¡¡ðº…†YÍÎ
þ
( BUK23
¢½î}öÍÎãäÿ[]°
%

%
T}
%

Ž²¤%Ö
$
!ƒºÑÒÏÐ,“$ŸÑ>܂.HÃ6w
Ö¤ž¤_’“
(
ƒYïÛ¤
BUK23
¢½î}öÍÎãäÑ
Ò$,靠$”£Ž
$
1Y¤ÿB”£Ž¤
1(Eâ:Ì/¤‚—
I)5
£…†¤ŒŽ
(
§.H•£¤gð
$
¢½¥EOåæ¤àð6»ö
÷
(
¢½@±/8ö÷¤`ø¥.
$
†^
2
¤ð¥Þ§
D§A¤†V±ôH•æ
!2A
¤gð
*)(+
)
¢½H•­¤p
õ`ø
3
!¤Á®ºï
$
H•Nn:ä?±²
$
•öø
־
!?A
¤gð6»ö÷
*4$+
)
¢½$¤[N%}`øH•
‰¥¦`$¤‡¤p<
$
•`–æ¤gðB6+÷
ã
*4+
)
¢½$¤:ø`ø
34
H•S¢g<¥¾¶Pß
$
¥S
tåæ¤àðB÷
$
:ø`ø
3
¯t8’…†$gŸt
¾NQFR_‚ƒ
(
ùe
$
¢½•[Nƒ1åæ
%
¯£åæ
d͛1åæ­B6»÷ã
(
üP,´º¢½¤Ë¾
ˆ‰
$
6îïŒK%ÁŽHâ½UV„ÑҌKŽ
%8.¹Ð
(
(X$Q
 c®()
!
 c®()
!.-SO,WSTUP.EUP0LP0Z
LO,R0-S-Z6$ 9:B
󒏴US ÿB%}«¬¾ý¤@
’“¤iVvð()
(
Ÿùú‚ƒÛ
$
ŸZK 6U
S
$
Ÿ0ÈÉ1Ã0Èɗ[ÿB¦5Ì¥Ž¤@’“Cì
.54$.
)$5
s
4
t ñ
&$
òñ
#
w
X-SF&$$ ;-+# 9TU,R$ )$5
!9:?$9:?
0¯ºUS ëì#î›Ó
$
s¾«ö›‚ƒ
!
½P
$
° 13Öaý&

¤@’“¸t
$
´US ÿB
K²¤Ì¥Ž„«¬¾ý
(
ƒº«¬•US îVö»
1ö«¤“µ
(
 c®()@±Ò-%}¤Ž6
US
$
ƒºYö1Œn«“¤©8°
%
c}¥ÑÒ
(
ÏÐ,“ý-
$
Ž“µõ¶XX
$
W䐰˜É
YÉBÙԌ°
$
ìÑÒc}¤fÍ
(
ŸŽn«
“‚6US
$
—[
9:?$
•µÎƒ
$
$ü$,Ž¤]
°©8°¥c}
(
ßï &
*4)+
Ÿ«ûüOý$”£
Ž_’“°±þ„°Œ‹¤#în«“°±û‚6US
$
ƒÃ0ÈPɗ[
9:?(
•²ç¹U°dhOìµÎ
!M8:3
B^G
ƒ
$
6+°c}.$,«ûüOý_ˆþ%“$
õ¤°±þ„°Œ‹
)
O”£Ž
(
wN_’“ÈÿÌ/¤ð“Ž
$
Ö¼6ŒŽK¦1ð
“åƒ5X&¼`AYɏ,
$
1ó¼6ȋÿ!AC—Œ

(
 c®()!Ÿ•n_’“6US
$
¦ÏÐ,“$
ÑÒ#în«¤ùP,“
$
¦A01¦Ù
%

%
¦ð“åƒ
5¤,“
( ]WT0Z
&
*44+
Ÿæ8 ÜA»6US
$
¦$,aH
þ%“$ÑҔt:Sê@Ž“µÛ+ˆÜ
(
=:€
&
*4&+
—[¢Ž3 c®@’“
$
¦$,qΚ$ÑÒ
¢Ž3„Œ#în«“
(
rn˜&
*45+
¦ûðÓ$°”
£Ž¸@™`
(
ö¼ºð“Ì¥ÍÎ
$9:?
T}Ž²²%¦
$
@’“Ž
µT}
$
ÎÜ
%
4
$
Φ4
%
¦¹&
( 9:?
•¦ÙœöÿBã
/¤ðùŽ
#
³¾ö˃iCºð“ö̎¤<=ø
$
•˜
e
%98
&Ø|ôWÔ²5+u
$9:?
ι!Ÿ×HK¦¤³
°
$
²²xô.°Oì
(
ÐA
$
 c®()[0¯[N

$9:?
´ºZK ¤«¬€¹º_’“îV
$

%ÁŽK¦
$
¯¦Ù©8#în«“¤»O
$
•,Ž¤
ö÷Ž0¯#Å
(
Z™!8^ƒ¤US Kb
$
¡¡Ë¾
û($™,Ãã$j‡ƒ¤C€
(
Äl&óŽ3´Ã0
ÈP
9:?
àð c
$
®ƒÑÒ36_ˆ
3

!(u$
AW
äÏÐ,“Ÿl%6
$
M¾¾¯l3œ$Šh‡ƒ_óg
Íâ
(
(XcQ
ŒKÌ¥Ô¹
!
šO´ºÏÐ,“‚ƒÛ„%Ö¤
j˜ˆ‰
$
§.ËÌ¥ÍÎÑÒUV
$
ãEÌ¥ÍÎUV
ÔWƒºÏÐ,“Ž¤ÑÒ
$
MpÜQÔÃÌ¥Í
Î
*4#+
%
¨©Ì¥ÍÎ
*4%+
%
øy° Ì¥ÍÎ&&
(
iĚO
Mz´ÏÐ,“–«¤uj
$
ÏÐ,“Ë44iCº¿“&
™,
$
AWä$,$šn,“
$
š™
$
Ÿ„Hf,“J!ÕW
ˆ‰áìI
(
ôº•n,“õB¨©¤`ø
%
E`n#îA
^Ì¥ÍÎ()¯•n,“ŽÑÒÃü:㲤
ðÏ
(
)Q
#1
Ì¥ÍÎÉó[O¦@¶¤,“Ž ÑҘÉ
$
Œ
$d]°
$
T}
$
LP
$
!í&ð֏6[O쀤,“ÑÒ

(
Ì¥ÍÎ¥œµƒ()ö#’
$
!Ÿ$ü¯ù
°
$
ÑÒ
$
c}[Ã_
(
Ì¥ÍÎÑҘÉåƒ,“¥‚ƒ
w֤̥‚ƒÑҍŽ 
$
6ÏÐ,“ŽÑÒ%8.
i¤Ð 
(
Ì¥ÍÎÑÒ()¤g‹Üݺ´,“‚ƒw
Ö¤¹Ðˆ‰
$
i66r,“‚ƒ–%8ÅN
(
šOåæ
g斁¤j˜ˆ‰
$
ãE,“‚ƒwÖWgü
$
»O
$
ãE
•ÏÐ,“güB÷¤iVÑÒUV˾:ü
$
Ïi6Ì¥
ÍÎ()¯ÏÐ,“ÑÒ$¤‡ƒ%8ãEçè•ÅN
(

ƒ„?…
#
* +!,-._P0TL-UPTSL--SDVOeOS-E*H+FH)# F
* ) +!
ºcX
F
Ì¥ÍΘɄ‡ƒ
*9+F
23
#
_N¤:¥‡
$
)$$# #F
* 4 +!

$
%yÁ
$
Éo6
$
&
+
üPð“3É´®ƒ$,¤Ñ
҈‰
*H+F
23A&²e
$ (#$ !# 4F
* & +!YT0Z8 a$ R`T-b$ T`0ZYH$ OLTSF]PZRS6DOSO,LPeOD,UOO0P0Z
-[LRO_P-T,LPeO,-.E-W0VDP0 ]W-7WO,TEDWSOWDP0ZP..-_PSP\OV

)
3TVUO0-,OEL-UT[P0PL6,RU-.TL-ZUTER6*H+ F20TSJP-,RO.$
)$&$ &5%!5 # F
* 5 +!
’.³
$
i&
$
$o
$
&
F

)3
ԓ`HÃÌ¥Í΄Œ
¯9ã÷ŽÑÒ$¤‡ƒ
*H+F
&@e
$ )$$%$ 5)
!# )F
* # +!$ OLTSFGU-0LTST[P0PL6
,RU-.TL-ZUTER6*PLR 98 VOLO,LP-0 -[LROSPZT0V _P0VP0ZV-.TP0 -[
??2>
#
UO,OEL-U# SPZT0V T[P0PL6D,UOO0P0ZT0V DLOUO-DOSO,LPeOSPZ3
T0V3.T,U-.-SO,WSOP0LOUT,LP-0*H+FH!## &F
* % +!
›‚
$
β¡
$
m(
$
&
F
ŸMHóô
>Z

6Ô¹¤Ì¥
Íέµ¤—[•WX‡ƒ
*H+F
$%,&²e
$ )$$$
&!5# &5F
* +!CPQG$ TEPV D,UOO0P0ZT0V PVO0LP[P3
,TLP-0 -[
!
3T.6STDOP0RP_PL-UD[U-.R%+&% D%&$(,(60/#WDP0Z
O0\6.O3P..-_PSP\OV .TZ0OLP,0T0-ETULP,SOD,-WESOV *PLR ]?C<
T0V 98*H+FH* ( +! R`T0Z2 $` QOG@$ CW HQ$ OLTSF8,UOO0P0Z
!
3ZSW,-DPVTDOP03
RP_PL-U[U-.0TLWUTSEU-VW,LD_6,TEPSTU6OSO,LU-ER-UODPD*PLR P.3
.-_PSPDOV O0\6.O-0L-E-S6.OU.-0-SPLR .-VP[POV _6Z-SV 0T0-E3
TULP,SOD*H+FG--V *$+!HPT0ZBG$ CPT0ZBB$ YT0ZQ]$ OLTSF:..-_PSP\OV ,TEPSTU6
L6U-DP0TDO.P,U-UOT,L-U[-UP0RP_PL-UD,UOO0P0ZP0 0TLWUTSO7LUT,LD
_6,TEPSTU6OSO,LU-ER-UODPD*H+FH?RTU.JP-.OV 20TS$ )$4$
&# 4#F
*+!9P0 Y2$ TEESPOV L-D,UOO0P0Z-[LU6EDP0 P0RP_PL-UDWDP0Z.P,U-UOT,L-U*PLR
LU6EDP0 P..-_PSP\OV _6ZSWLTUTSVOR6VO*H+F20TSJP-,RO.$ )$4$
&4!# 4)F
*)+!C-EODXPSOST2G$ 8PSeTH:$ SP\OV ,R-SP0ODLOUTDOD,TEPSTU6UOT,L-UD-03[S-*D,UOO0P0Z-[DOSO,3
.#4$.
¾Gn&
#
̥ͷƒºÏЍŽÑÒ¤ˆ‰Š‹
LPeOP0RP_PL-UD*H+FH*4+!
mn
$
¥ÞÞ
$
ÉÌ)
$
&
F
Ì¥ÍÎÉÑÒ$,$t€
<`‡_.‚—
*H+F
$%&
$ )$$($ 4!# %#$F
*&+!
!?Û
$
´ËX
F
MtÞø`øð“ÍÎþ¤Ž¾ˆ‰„‡
ƒºÝÞß$Ž¤ÑÒ
*H+F
_@e
$ )$$ !(#
(F
*5+!]TV/.-RT..TVP9$ 8TSTU69+JP-ETULPLP-0P0Z.P,OSTU,RU-.T3
L-ZUTER6*PLR D-VPW.V-VO,6SDWS[TLOTDTEDOWV-
!

3T,PV ZS6,-3
EU-LOP0 L-LROEUOVP,LP-0 -[EU-LOP03VUWZ_P0VP0Z*H+FHL-ZUJ$ )$4$ ()!#5$F
*#+!XWPZ0POUb$ @WPSTU.OA$ XOWLRO6HC$ OLTSF]PZR EOU[-U.T0,O
T[P0PL6,RU-.TL-ZUTER6!]?2< TDTRPZR3LRU-WZREWLD,UOO0P0Z
L--SP0 VUWZVPD,-eOU6L-DLWV6VUWZ3ESTD.TEU-LOP0 P0LOUT,LP-0D
*H+FH?RTU.JP-.OV 20TS$ )$4$ %& !4 #)$5F
*%+! R`-W -ST0V P0LOUT,LP-0 *PLR A;2*H+FHMSO,LU-T0TS#&)F
*+!8W aQ$ ]W C]$ b-0ZC$ OLTSF2[P0PL6,RU-.TL-ZUTER6*PLR
P..-_PSP\OV A;2DLTLP-0TU6E]82O[-U_P-S-ZP,TS[P0ZOUEUP0LP0Z
T0TS6DPD-[LUTVPLP-0TS)$$%$ 5)F
*(+!
˜Yì
$
$
r:t
$
&
F
…†YÍÎ()ƒº$,Ž
ÑÒ¤ˆ‰Š‹
*H+F
$™,
$ )$$$ 4(!%#4F
*)$+!YT0Z<]$]OC<$YT0Z;$OLTSF8,UOO0P0ZT0LP3P0[ST..TL-U6
,-.E-0O0LD[U-..T,U-ERTZO=,OS.O._UT0O,RU-.TL-ZUTER63-[SP0O3@<=98 .OLR3
-V*H+FH*)+!CPW H$ YT0Z8 <$ 8W0 HQ$ OLTSF8,UOO0P0Z-[-DLO-T0TZO0ODPD3
T,LPeO,-.E-W0VD[U-.7/$)-%+% 8%%-)&##@O-UZP_6R?AC<=
<9<3-0SP0O3]?C<=98*H+FGPL-LOUTEPT$ )$&$ (4# $5F
*))+!TS]OE@)=,OS.O._UT0O,RU-.TL-ZUTER6=.-0-SPLRP,,-SW.0=
LP.O3-[3[SPZRL.TDDDEO,LU-.OLU6D6DLO.[-UD,UOO0P0ZT0LP3LW.-U
,-.E-0O0LD[U-.ROU_TS.OVP,P0OD*H+FH)&)# #%F
*)4+!
!ï³
$

$
<¤µ
$
&
F
ƒ¦¬
M@G>
…†YÍÎ
3
]?C<=98
ƒ]°ÑÒò$”
M@G>
Ž
*H+F
$%
&
$ )$$$ &$# %5$F
*)&+!8W0 9$ >O0 H$ AW ]$ OLTSF2,-._P0OV 2&4 ,OS.O._UT0O
,RU-.TL-ZUTER6T0V -0SP0ORPZR EOU[-U.T0,OSPcWPV ,RU-.TL-ZUT3
ER6=.TDDDEO,LU-.OLU6.OLR-V [-UD,UOO0P0Z,-.E-W0VD[U-.L-LTS
TSKTS-PV -[>TVP7*H+FH
*)5+!CP9$ YT0Z8 <$ R`T0ZQ9$ OLTSF20 -0SP0O,-WESOV ,OS
.O._UT0O,RU-.TL-ZUTER6*PLR C<=98 .OLR-V [-UD,UOO0P0Z,-.3
E-W0VD[U-.@,&$/0 %+0(%)-AO_7FT,LP0Z-0 XM@G>3)
*H++H?RTU.JP-.OV 20TS$ )$$$ 54!&# $#4F
*)#+!AP0Za$ .O._UT0O,RU-.TL-ZUTERP,,-SW.0*H+FH45(# 44$F
*)%+!]T0\TSJT6OU9G$]T0,-,K HGFCPEPV UT[LDT0V .O._UT0OLUT[P,
*H+FGMJ8 COL$ )$$%$ 5# )$(F
*)+!B-0Z8 8$GW 9$.TL-ZUTER6[-UD,UOO0P0ZT0LP3LW.-U,-.E-0O0LD[U-. R%-%
(&)&##*H+F*)(+!9TVOETSPb$ CTKDR.T0T$ 8W_R-/PL>$ OLTSF2.6S-PV-ZO0P,EU-3
,ODDP0Z-[2??P0 SPEPV UT[LD*H+F E^O0 JP-SH$ )$$$ 4# )F
*4$+!GT_OS-;$ 9TULy0 X$ @T_UPOS8$ OLTS+8OeOUOTSLOUTLP-0DP0 SPEPV
,-.E-DPLP-0 -[GU-0LTS<-ULO7SPEPV UT[LD[U-.ETUKP0D-0wDVPDOTDO
T0V P0,PVO0LTSETUKP0D-0wDVPDOTDO*H+F9-S9OV$ )$$ % !(=
$ # $%F
*4+!@-0\TSO\9W0-\M$C-EO\:ZSODPTD<$[W0,LP-0 T,,OSOUTLODZSW,-DOLUT0DE-ULOU& T0V P0DWSP0 UO,OEL-UVOZ3
UTVTLP-0 P0 4B43C TVPE-,6LOD*H+FM0V-,UP0-S-Z6$ )$$($ 5$
!# 4&(4F
*4)+!
ßï 
$
¨­
$
b¼B
F
 ®cÌ¥ÍΕµÎƒ$
ü$™,Ž°c}[Ã_
*H+F
_e
$ )$$)$ #$
!4# 45F
*44+!]WT0Z9a$ ?T0ZY 8$ R`T0ZH$ OLTSF2LTUZOLT0TS-ZWOP.3
EUP0LOV E-S6.OU[-ULROUO,-Z0PLP-0 -[T0LPESTLOSOLT,LPeOP0ZUOVP3
O0LDP0 >TVP78TSePTO9PSLP-URP\TO_6C<398398*H+FH?RTU.T3
,OWLJP-.OV$ )$)$ 5# )F
*4&+!
=:€
$
b¼B
$
¯
F
¢Ž3 c®@’“îöw-
qΚ$¤¢Ž3„#în«“
*H+F
$%,-.
$
)$$$ &5!# 5%&F
*45+!
rn˜
$
ɀ…
$
ºø*
F
 c®îöw-É%-ûðÓ
$¸@™`
*H+F
_NŠ‹
$ )$$$ )(!)# )(4F
*4#+!
²
$
J. 
$
pÜQÔÃÌ¥ÍԈ‰Š‹
*H+F
ÍÎ
$
)$$($ )%!5#55#F
*4%+!
½Ø
$
½ž
$

$
¨©Ì¥ÍÎ%ÁŽÆ§$,˜{+
«$¤Ê’ô
*H+F
ÍÎ
$ )$$#$ )&!4# )&4F

†‡-0
!
Ž
#
.%4$.