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作 者 ：宁颖,孙建,吕海宁,屠鹏飞,姜勇

期 刊 ：中国中药杂志 2013年 38卷 12期 页码：1938.

关键词：赤小豆；化学成分；结构鉴定；

Keywords:Vigna umbellata, chemical constituents, structure elucidation,

摘 要 ：通过大孔吸附树脂D101,正相硅胶,Sephadex LH-20,ODS,反相HPLC等多种色谱分离方法相结合,从赤小豆70%乙醇提取物中分离得到8个化合物;借助ESI-MS,NMR等光谱技术鉴定其结构为2β,15α-二羟基-贝壳杉-16-烯-18,19-二羧酸(1),2β-O-β-D-葡萄吡喃糖-15α-羟基-贝壳杉-16-烯-18,19-二羧酸 (2),2β-(O-β-D-葡萄吡喃糖)atractyligenin (3),3R-O-[β-L-阿拉伯吡喃糖基-(1→6)-β-D-葡萄吡喃糖] 辛-1-烯-3-醇 (4),(6S,7E,9R)-6,9-二羟基-megastigman-4,7-二烯-3-酮-9-O-β-D-葡萄吡喃糖苷 (5),刺五加苷D(6),白藜芦醇(7)和麦芽酚(8).结论:化合物1~7均为首次从该属植物中分离得到,化合物8为首次从该种植物中分离得到.

Abstract:Phytochemical investigation was carried out on the seeds of Vigna umbellata. The 70% ethanol extract of the seeds of V. umbellata was subjected to silica gel,Sephadex LH-20,ODS column chromatographies and preparative HPLC. The structures of the isolated compounds were elucidated on the basis of NMR and ESI-MS spectroscopic data. Eight compounds were obtained and identified as carboxyatractyligenin (1),2β-O-β-D-glucopyranosyl-15α-hydroxy-kaur-16-ene-18,19-dicarboxylic acid(2),2β-O-(β-D-glucopyranosyl)atractyligenin(3),3R-O-[β-L-arabinopyranosyl-(1-6)-β-D-glucopyranosyl] oct-1-ene-3-ol(4),(6S,7E,9R)-roseoside(5),liriodendrin(6),resveratrol(7)and maltol(8). Compounds 1-7 were isolated from Vigna genus for the first time,and compound 8 was isolated from V. umbellata for the first time.

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