作 者 :闫冲,林励,刘红菊,林志新,陈盘余,蔡聪,郑来安
期 刊 :中国中药杂志 2011年 36卷 22期 页码:3130.
关键词:檀香叶 ;黄酮 ;化学成分 ;鉴定 ;
Keywords:Santalum album , flavonoids , chemical constituents , identification ,
摘 要 :目的: 研究檀香Santalum album 叶中黄酮类成分,为檀香叶的资源开发提供理论依据。 方法: 檀香叶的70%乙醇回流提取物经大孔吸附树脂、聚酰胺、Sephadex LH-20等柱色谱法分离纯化,现代波谱技术鉴定化合物化学结构。 结果: 分离得到8个黄酮类成分,分别鉴定为芹菜素-6,8-二-C-β-D -葡萄糖苷(1),牡荆苷(2),异牡荆苷(3),荭草苷(4),异荭草苷(5),白杨素-8-C -葡萄糖苷(6),白杨素-6-C -葡萄糖苷(7),异鼠李素(8)。 结论: 所获得的8个成分均为首次从檀香中分离得到,其中7个为结构相似的黄酮碳苷类成分,并形成了3对同分异构体。
Abstract:Objective: To study the flavonoids from the leaves of Santalum album . Method: The sample was extracted with 70% ethanol by continuous thermal reflux. The extraction was separated and purified by column chromatography over macroporous adsorption resin, polyamide and sephadexlh-20. Their structures were identified by detailed spectroscopic analysis. Result: Eight flavonoids were isolated and identified as vicenin-2 (1), vitexin (2), isovitexin (3), orientin (4), isoorientin (5). chrysin-8-C-β-D -glucopyranoside (6), chrysin-6-C-β-D -glucopyranoside (7), and isorhamnetin (8). Conclusion: All compounds were isolated from this plant for the first time.
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