免费文献传递   相关文献

Advances in determination of multi-residue pesticides in traditional Chinese medicine by GC-MS

中药中农药多残留气质检测方法研究进展



全 文 :rÇrðǑGHI[J&…©ƒ„EF
¹àÀ
#
Å
!
#
ô%¥
!
58E¬F¬G ßàãÐE¬G HäåbIJÞ
#
ßà
RMMR`Q
$
ƒ;
%!
CrÇrðÇGHI[J&†“[µ$
#
*^‡hÖ¤…©EË&60
!
>C–÷;€Fµ;[ðÇGHhÖ
¤…©üùjZý$©
#e4-.-31
…©
#
s[ùj6þý$‡ùÓEË&}…
!
60ª\“±-

L®Çk}…rÇrð
ÇGHI[J&…©
!
>¤Cªn´[±-
!
CªrðÇGHJ&r[DEË&6

$
„…†
%!

&
ðǑGH
&
I[
&
J&
&
hÖ¤
$
8‡$f
%!XMRMMQQRMMN
$
ˆ‰Eq
%!
­æ
.
k¡÷‹Ç÷Ü
/
øùk¡­u
$XMM`d+M`LMX<
MX\%&
­æ
.
!|Ê
/
øùߦ/§uv
$XMMN7>;LL7MX%
$
Š>‹
%!
!
ÿõ
!
ƒ„m
!
‚&³ÙrÇèéÚ6G°ò̃„
!
A(&,$MRM%YXN`LM\Y! -$
>‹š›
%!
Dþð
!
]jƒ„ã
!A(&,$MRM%YXN`LM\Y!-/)*H)*RRMR]0)$fG/I
!!
ðÇGHÿrÇÁKßJ&[k&À
!
¿­V£CE
KßÇÁðÇGHÀ,&§Þ2Å
!
hÐhò­ÇÒ¹C
ÌrÇÁü¼†ÑQ!rg(ðÇGH·&ԅ©EË
ÓÔ

ò­è‰rÇÁrðÇGHÀ,0¾€m­æ
!
ªÈ
$]•rÇÁðǑGHJ&[À,…©ƒ„†Ë

Ij
[ÿ¹“ùÓ±ÌS“•6˜)Î2k
#
ԝ͔
#
Í
BÙ6\·e[ ´
!
$LIj
<
[ÿJ&…©ÿrÇÁr
ðǑGHJ&ùӀF[–ë²Ê
!
hI[¹“ùÓ§#
ڐ
!
Xêò­rÇÁðǑGHJ&À,…©[CD
!
µ
ò­rÇÁðÇGHJ&cºµq–&[ùÓßJ

$
L$FCrÇrðǑGHI[J&…©ƒ„í´EË
Ϣ

!
ðǑGHI[J&…©hÖ¤ùÓ
!_!
µ$…©
!
$å[ðǑGHµ$…©‚&wxW€
µ$©
#
%&µ$©
#
uµ$
#
ŸÛ˜µ$‡

^(…©[
ÐZ-ÿ͓¡·èl‡Û
!
ªY~]•¶·E
!
†è¡
·ÐµÌ
!
×E|`6s*^
!
‡ÛS(·æ¡Éyè<


vh‹[µ$ùÓÑÍ`€FÑ\“
!
ðÇGH6
»˜ÇR9
#
RP
#
)o
#
Tg‡Û“·‡›N&Ô[…†€
F
R
ŸXšçÿý$[–-ÿs£_¸¹&͓èl‡Û
!
yH›N
!
i¶·Qý$.&Ù6
!
>X)ÎÚ6T8`
¢et(
!
i¦T*EnÊ^
Q<_(

hZ˜+}µ$©i$
åý$…©jå
!
yèý$9’,
!
‡Û“·g
!
*¦T‘
ÍBZ9ý$
!
Tg&‡Û°ò[±-
L<\(
!
µ&ÍBhÖ
¤él
N(

aN‡Ûý$ÊJl
#
93(iuµ$jÐ
!
*ô~‡ÛS(·¤¡[uµ$џۘµ$

!_#
*^…©
!
$å[*^…©‚&wxˆ
<
ˆ6^©
#
I
-}ÿ©
#
.^©

ªrˆ
<
ˆ6^©Í“‡Û·¡
!
ý$
9’z
!
`/01

I-}ÿ©ÚÊÝ-nÊ^t(e
!
klæE
!
`/01

.^©*EyH
!
*^éŒ2@
!
ì
&ÔB¢¹&•^^^
$7.%#
334
$TTA%#
ʺ5sw
‡g(6BèlºðÇB¢

ùjý$
$18-%
©²×ÍB·g
!
¸¹&!^T%
!
Ê
Jl
!
kT÷
!
hÉ7•nÊ^*E
!18-
8-X$ô$
å[ˆ
<
ˆ6^Ñ-}ÿ©CÍBEË*^Ñ>¤

7
«
Y!`2“ùjý$©Ö¤ÍB
!
93(G,/(æ
!
*Ey7
#
›N
!
èl‡Û“·g
!
èޕ-Aiõ‡

RÝ8;}ÿùÓÿ\“•ðÇGH6r ªµ$
ÌiðÇ[|¢›N6s*^ùÓ

¢_
!
ð8ÑABrð
ÇGH&Ô tr͓æ8
RX!
ˆå­‡6“RÝ8;}
ÿÑ
6&/%0&
8-*^
!

@<=1
Z9J&
RM¢ðÇ
RL(

L®è2“RÝ}ÿà^
!
CD&vv¶rèlº
#
èl
Ï
#
ôstBšÑ9.³¶šª‡
QX
¢ðÇGH[6
…©
RY(

!_$
ùjZý$ùÓ
$18=-%!
ùjZý$ùÓÿ]ùj
ý$s¨_€Fµ;[|¢‹[ý$6sùÓ
!
ª*E t
yH
!
-×*^

vh
18=-
ý$.&Ì*iIj}ÿ6
6sùÓ¹“
!
S“•6Ê€èlÌ

I•½ÿ|¢-
‡Ûý$ùÓ
!
>yè*E9’,
#
ÍB“·g
#
kl÷
#
93(
#
JK&e‡–-
!
S“•ˆî
#
ùî
#
Iîr[Ê
€èlÌ
#
nʀèlÌi-lÌ[6
!
]ðÇGH
6rè¤÷[\“h˜
R\
vh]rDžV
!.F$)*
‡
XM(
®“ùjZý$
#
Ij}ÿ|[ÿ¹“ßJ&&r†
ÇrèlºðÇ[GH ´
!
0Œ¼.L…©Y¹µ&Í
B&Ô[élhÉ®R&¡·[èl‡Û

!_%
s[ùj6þý$ùÓ
$=18T-%!
s[ùj6þý$
ùÓÿXS·[ùjý$ÁÂ
$

!
;r<:U
!
RN
!
N
‡
%
iÍB|µƒ=`[ûÄÌEê>ÂÝ-
!
뾶·
-Y`Q-
{
QY
ï{
_
—
XMRR
÷
X
´
!!!!!! ! ! ! ! ! !!!! ! ! ! !
U/&fQY! ;004(!_
J(P%4$%B! XMRR
SÄ[‡ÛÞ(-F
!
X¿¢.&Ì(Œ
!
ª–-ÿÍBµ
$
#
*^|`ŸÚ
!
Y×&EË?@
#
A*
#

#
ÍBM`‡
*E`/
!
S“•¿¢6F01і[ðǵ$*^
!
d
ùÓ¢P“•ÊÌ٢ͣrÇÌ[µ$Ñ*^
!
vhÑÍ
]Ÿž
#
cŒ‡s[rðǑGHJ&8Î͓
XR!
h]
rÇÁrðǑGH&Ôrbè²BG
A$)*
‡
X_(
®“:
ݳês[ùj6þIÛ
!
âÐEê(ŒÛCC6
#

rðÇGHE˵$*^
!
ÊJlê
NMfYQh gRRMfRh
L
®
!
“s[ùj6þý$
<
Ij}ÿ©b*Z9J&±’
rʺ5swGªô”ÌGH
XL
!_&e4-.-31
©
!e4-.-31
©
$e4GW!-$0B!-6(G2E(!
34**(5 $)5 1$6(%
i{›N
#
y7
#
[·[CðǑGHE
Ë6

è2K
!
Ñè
XMM
é¢ðÇGH*“d…©E
Ë6
X\(
e4-#-31
…©ÿ“DECCÒ-˜FD“s
á7[ÍBEËWµ
!
ØaÒ-cABGiº^H%&
!
s
áÍª64
#
§¾EË6þùjý$
!
ÕXWµˆM`h

81>
IÛ
#
ABG[-˜FD“sá7r
!
sá¾$
_óˆhnÊEÍI¾&Ô

*^Û
81>
›æaÒ`µ$
ˆr
!
i$å[ùjý$©jå
!
*®Ü¡·-p^ÑÞ(
²×[‡Û
!
>*®RÝ-9’

7«2“d…©&ԟ
žr
RM¢ðÇGH
XN(
!
뼇b“
e4-#-31
©I[&
ÔJKr
RX
¢ðǑGH
X`(

d©Y¹]ðäBðǑ
GHÌJ&[ÍBnÖ¤rè8Î[\“
!
ªbX]rÇ
rðǑGH
#
-kÍBðǑGHÌJ&
#
ðäBLÇJ
&GãÌÍBÇÌJ&[nÖ¤‡¯°`¾ê8M[“e’

#
rÇrðǑGH&ԅ©
000
Ij
<
[ÿ¹“©
]rÇÁrðG&Ô9
!
††N`ÍB˜)Ρ
!
Ö
¤ t01
!
ÊJle‡D

‘k[ÿ
@<=1)
ùÓ[€
Fêl¥ÍBZ·ðÇԝԷ6™O&‹äq

|k
[ÿm O‘’Æš
$J4&0G$)%
/ÔðÇKXI!
QM(
!
¶·
sF‘’Æš
$1;=%
®“^ÄÌ[±ísFEËԝÔ
·
!
Z9®“9’WtёmJ&XYiŸO6s[Ðç
K̟O6™

ýk[ÿ
$@<=1[=1%
¶·vÀ^ÄÌ[
±ísFê°sF
!
CªEËÍáPQ
!
“ªFsFfÿE
|`/Æ6C%[01

ª‚&±-ÿ]µ6iP
[s¨_µq~{[01ni
!
“•01ԝ
!
±ÌS“•
6˜)Î2k
#
ԝ͔
#
ÍBÙ6\·e[ ´
!
$L
8Î\“•Ú6l¥[rÇÁr[ðǑGH&Ô
@<
=1
©&ÔrÇÁrðǑGH[\“7«
!

R
¼
R!
rÇrðǑGHI[6…©
ÇÁ¢ª ðÇ¢ª µ$…© µ$‡Û *^…© (ŒÛ &ԅ© 7«
!
ÁÄ
#
Q!
#
¶¯
#
Ð;
!_M
¢èlº
#
è

#
ôstBš
#
9.³¶šªðÇ
%&µ$ „ºt
<
âÐ
$`LkL%
;r<:U »R
<
âÐ
$NLkRL%
@<=1 QR(
vv¶
!QX
¢èlº
#
è

#
ôstBš
#
9.³¶šªðÇ
ŸÛµ$ DE
@8
SBDš
,
-R
$RkR%
@<=1 QX(
vF’
RL
¢èlºðÇ %&µ$
!
»R
<
âÐ
$NkX%
;r<:U »R
<

$`LkL% @<=1 QQ(
!
\câ
#

#
)ºâGqârÇ
!X`
¢èlÏÑè
lºðÇ
!
\câ%&
\\⠟Û)
ºâG\qâ
TžŸÛ
!
âÐ
<
ýºt
$QkX%
âÐ
<
c
$XkR%
xqã
<
âÐ
$XkR%
;r<:U xqã
<
âÐ
$\kQ% @<=1 Q_(
«’
N
¢èlÏðÇ ŸÛµ$ xqã
<
âÐ
$XkR%
;r<:U
@<=1 QL(
UVL
èlÏðÇ %&sá© âÐ
!
;r<:U-
}ÿ©

<
xqã
$_kR% @<=1 QY(
«W’
L
¢èlÏðÇ ŸÛµ$ xqã
<
âÐ
$XkR%
pÿ
@<=1 Q\(
JK
RX
¢ðǶšª
e4-#-31
© DE
81> S @<=1 QM(
tU¯
R_
¢èlÏðÇ TžŸÛµ$ âÐ ;r<:U »R
<
âÐ
$RkR% @<=1 RM(
!

#
²X
#
Q!,Z’Ñ
Ð;
!XR
¢èlÏÑô
stBšªðÇ
Z˜ý$ DE
<
âÐ
$Qk\% !
rÔ^ø
#
;
r<:U*^
!
ýºt
<
âÐ
$`kR%
@<=1 QN(
±’
RN
¢èlºðÇ Œ[ DE ;r<:U âÐ
<
»R
$Rk`% @!
¡B#
Ú
6 ì
#
! Y
#
ZÒì
L
¢èlÏðÇ W€ º[
S S @<=1 _M(
Ï!R¢èlºÑô
stBšª
ŸÛµ$ »R
<
âÐ
$RkR% !J&/%0&
:\UÑ
rÔ^øûÄ}
ÿ-
!
»R
<
DBDš
$`LkL%!
»R
@-\`Q-
{
QY
ï{
_
—
XMRR
÷
X
´
!!!!!! ! ! ! ! ! !!!! ! ! ! !
U/&fQY! ;004(!_
J(P%4$%B! XMRR
!!@<=1[=1
C•ðǑGHJ&]rÇÁr2jC
æg
!
ìÿ]Ó]џžs[r\“^‘

7«26“6
þùjý$
<
Ij}ÿ
<
_¹[ÿ
$e4-#-31<@<=1[=1%
C
D&Ÿžr
RM¢ðÇGH·[6…©
!
ªÊJlæ÷
!
iæ÷Q›¾£hÚ6jÐl¥[¡Œs[–5KT[)
ΏD

ªàðäBr[ðÇGHIj}ÿ
<
_¹[ÿ6
bè2
_X<_Q(

_¹[ÿi{#.˜)Î
!
S“•ÔÍ
”
#
ÍBÙ6\·e”&Ô[ÍB
!
]§¾[rÇÁðÇ
‘GH6rʖæ€Ê¤¡E“

$
rÇÁrIj
<
[ÿJ&ùӎ]D
Ij
<
[ÿ¹“ùÓr[ÿêm“âJ&à
!
C¥[[
v\¬åæ¡

rÇÁÚ6l¥
!
ÍBr[‘¢ðÇGHJ
&s[)Îæ¡
!
$LÍBhÖ¤¬ëÿ`±aÚ[D

L®|(ðÇüèlϪ
#
¶šª‡ðÇs[é\æ
¡

ðÇGH6 tr[s[é!
ÕÍBr.6Ì
®[ªàs[Ú62kuvJ&0Œ[,/
!
wxs[Ö
4Ñs[T5é__(
vhCLD[ƒ„6“s[b^À
,‡ˆ=»
#
À,1a
#
‘k*^
#
å/…©=»‡
_L<_Y(
hC
•9¢s[͓ªs[b^À,‡ˆ=,ÿvh­3_ƒ
cs[é\¢ê†[|¢…©
!
ì^¢…©\“•†ÓJ
&·ªÿè¡·.&ÍB[¦§C褑†d
!

,

Bg’EG¤¡
!
yèYZ[s[±
!
]69×&ÜÝ
C\•¿ÍB[s[b^ÀÍ
&
%×&¡·evÍBÁÂG
.P
&
&^¢ÀÍ[z—eԝ^E
&
¾‘[ÍBs[E
Ò`ßàÐr
!
Öa&Hå°òlæѤw“

vhè2®“1a6Awۅ©;T8ÍBs[
é_\(
!
-דfÍBs[g’[EG
!
¸¹&I•s[
b^•µ[Y7
!
Z9^¢…© m 1aAwۃcs[
é\CÔ·äã[.E
!
·e&JK&
!
µ&J&Ç
Å(

yHèé[hÖ¤ùÓсÇÅ([ðǑGHJ&
ùÓÿðǑGHJ&[€F²Ê

$L
!
”;ðÇGH6
[€Fÿ†ÍBÜÝÑhÖ¤[›N^
#
*EyH^
#
e
Ú£
#
hÖ¤iJ&|ÿ^…†€F
!
jnY£ðÇGHI
[&Ô[‹ùÓ
#
‹…©Xæ8Î\“`‘ðÇGH[J
&r

$
ŒŽ
%
R (!
²÷Ú
!
gDN
:
ò­ðÇGH6ùӀF¡¢
9(:
ðÇ
ø_i7¤
! XMMX!XQ$X%, RQ:
X (!d#$)*.! #() dC! a$)*@1! (2$&:=G%/F$E(V%(2%($2I()2
$)5 *$0G#%/I$2/*%$V#BG5(%(054(0) /)/)9(:J//5 #(I!XMMN!RMN$R%, QXX:
Q (!D%(4b*3!D/)(GW(>!7$#$5%=:,0(/604V(%G%2G$&6&45 (K<
2%$G2/) ) 2#($)$&B00/6V(02G5(0) 0/&9(:97/G#(I7/<
V#B0=(2#/5!XMMM! _Q$R[Q%, _MQ:
_ (!d4) U@! a$%F$W(9.! 7GG#:J$0204V(%G%2G$&6&45 (K<
2%$G2/) $)5 #*#<%(0/&42/) *$0G#%/I$2/*%$V#BF2# (&(G2%/)24%($)5 6&$I(V#/2/I(2%G5(2(G2/) 6/%I4&2%(054(0G%(())*/6
/%*$)/G#&/%)($)5 /%*$)/V#/0V#/%40V(02G5(0) 7%$b&10I(<
5G)$&V&$)209(:9#%/>! XMMQ! `NL $R[X%,RL`:
L (!
hU
!
鸸
!
ˆi5
!
‡
:
Z˜+}ý$|ùjZý$|I
j}ÿ©&ÔÏ\r[èlºÑ9.³¶šðÇGH
9(:
}ÿ
!XMMY!X_$Y%, YQY:
Y (!
¿Þ\ ëjk ÞlG
:
r†ÇrèlÏGôstBšªð
ÇGH·[
@<=1

9(:
6ç§C
!XMM\!XY$Y%, NR:
\ (!@$%5/J%()G# >! =$%2l)(bU5$&9C! %4b1G&$>T! (2$&:
=4&2%(054($)$&B00/6/%*$)/G#&/%)($)5 /%*$)/V#/0V#/%40V(0<
2G5(0) I40G&(/6G#GW()!V/%W $)5&$IP PB*$0G#%/I$2/*%$<
V#B<2%V&(^ 4$5%4V/&(I$000V(G2%/I(2%B9(:>)$&#I>G2$:
XMMY!LLN $R[X%, _X:
N (!
1û…
!
ˆ,>
!
ˆþN
!
‡ Ij}ÿ©›NJ&4m\rè
lº¶šªðÇGH
9(:
ABø_
!XMM`!QM$RN%, QXQ:
` (!
¤nz
!

!
ptª
!
‡
:
ùjý$
[@[=1
&ÔtU¯r
èlÏðÇGH·
9(:
r­Ç_¥¦
!XMM\!_X$X_%, R`MR:
RM(!
ˆqq
!
0Ë]
!
rst
!
‡
:
ùjý$
<
gÔ7Ij}ÿ©&
Ôu’
#
9ór
RL
¢èlºðÇ[GH·
9(:
v™Çø¡
__2
! XMMY!XQ$RX%,\\Y:
RR(!OW#$0#=! D2$*$F$a! >W4204 D! (2$&:3$V5 I(2#/5 6/%2#(
5(2(%I)$2/) /6RNM V(02G5(%(054(0) 6//50PB*$0G#%/I$2/*<
%$V#B[I$000V(G2%/I(2%B$)5 6&$I(V#/2/I(2%G5(2(G2/)9(:9
8(02G1G! XMML! QM$_%, QYN:
RX(!C4 C7! .$0#aD! e) a8! (2$&:T(E(&/VI()2/6$42/I$2(<
5/)&)(*(&V(%I($2/) G#%/I$2/*%$V#B*$0G#%/I$2/*%$V# I$00
0V(G2%/I(2%B6/%I($04%)*I4&2%(054$&V(02G5(0) $*%G4&24%$&
V%/54G209(:9#%/7! XMM\!N_L$XY%,YR:
RQ(!1 )G#(b>@!=$%2/0?3!7$&(02(%/0-:=4&2%(054($)$&B00/6
V(02G5(0) /&E(/&PB*(&V(%I($2/) G#%/I$2/*%$V#B6/&/F(5
PB*$0G#%/I$2/*%$V#B2$)5(II$00<0V(G2%/I(2%G5(2(%I)$2/)
9(:>)$&#>G2$! XMMY!LLN$R[X%,LQ:
R_(!.4$)*de! Ca9! #() 7! (2$&:1I4&2$)(/405(2(%I)$2/)
/6RMX V(02G5(%(054(0) #)(0(2($0PB*$0G#%/I$2/*%$V#B<
I$000V(G2%/I(2%B9(:9#%/I$2/*%7! XMM\!NLQ$R[X%,RL_:
RL(!
ˆå­
!
wËx
!
ëky
:
Ij}ÿ
[
sFz[ÿ
<
¶·sF…
©Z9J&¡{rÁ¢ðÇGH
9(:
6^_
!XMMY!Q_
$_%,_L_:
RY(!
M|}
!
ÛåÎ
!
”KB
!
‡
:
aN‡Ûý$
[
RÝ8;}ÿ
<
ùjý$*^
[
Ij}ÿ
<
[ÿ©&ÔÏ\rGH[
QQ
¢ð
Ç
9(:
}ÿ
!XMMN!XY$R%,R:
R\(!d#4 J! 34$) c .! .(=.! (2$&:>VV&G$2/) /60/&5IG%/(K2%$G2/) 6/%2#(5(2(%I)$2/) /6/%*$)/V#/0V#/%40V(02<
G5(0) 2(K2&(0PB*$0G#%/I$2/*%$V#BF2# I$000V(G2%/I(2%B
9(:>)$&#I>G2$!XMM`! YLM $X%,XMX:
RN(!/%2m0<>*4$5/1! 1n)G#(b<=/%2/?! >%(P/&$J9! (2$&:J$02
0G%(())*/6V(02G5(%(054(0) 6%42H4G(PB0/&5(K2%$G2/) $)5 *$0G#%/I$2/*%$V#BI$000V(G2%/I(2%B9(:J//5
#(I! XMMN!RM\ $Q%, RQR_:
R`(!d$IP/)) @! e4)2/=! U(2%/?T! (2$&:1/&5-N`Q-
{
QY
ï{
_
—
XMRR
÷
X
´
!!!!!! ! ! ! ! ! !!!! ! ! ! !
U/&fQY! ;004(!_
J(P%4$%B! XMRR
(K2%$G2/)<*$0G#%/I$2/*%$V#BI$000V(G2%/I(2%B, $6$02$)5 0I<
V&(0G%(())*I(2#/5 6/%2#($00(00I()2/6/%*$)/V#/0V#/%40V(0<
2G5(0%(054(0) F)($)5 6%42H4G(09(:J//5 #(I! XMM_!
NY $X%, XY`:
XM(!.F$)*7.! C((=3:1/&5#&/%)(V(02G5(%(054(0$)$B00) #)(0(#(%P$&6/%I4&$2/)0
9(:9#%/I$2/*%>!XMMM!N`N$X%,X_L:
XR(!>&P(%/7! 1o)G#(b<7%4)(2(! T/)/0/>!(2$&:T(2(%I)$2/) /6
#(%PG5(%(054(0) H4G(PBI$2%K0/&5*$0G#%/I$2/*%$V#BI$000V(G2%/I(2%B9(:9#%/I$2/*%>!
XMM_!RM_Q $X%, RX\:
XX(!#4 +@!.4 +d!a$/.a:T(2(%I)$2/) /6XYY V(02G5(%(0<
54(0) $VV&(H4G(PBI$2%K0/&5I$2/*%$V#BI$000(&(G2E(5(2(G2/) 9(:9#%/I$2/*%>! XMML!
RMYQ $R[X%,XMR:
XQ(!?$E$%/=! 8Ga!=$%?3!(2$&:>VV&G$2/) /6I$2%K0/&5<
V#$0(50V(%0/) 2/2#(5(2(%I)$2/) /6$)(F*()(%$2/) /664)*<
G5(0) 6%420$)5 E(*(2$P&(09(:9#%/I$2/*%>! XMMX!`YN
$R[X%, XMR:
X_(!A$)*J! a4(a! .4$3! (2$&:=$2%K0/&5G%/(K2%$G2/) $)5 5(2(%I)$2/) /6V(02G5(%(054(0) I(5G)$&
#(%P0PB*$0G#%/I$2/*%$V#BF2# $)2%/*() V#/0V#/%405(2(G2/%
9(:9>00/GO6>)$&#(I! XMMY!N`$X%,_`N:
XL(!
ë:
!
rñJ
!
D‹x
!
‡
:
s[ùj6þý$
<
Ij}ÿ©Z
9J&±’rʺ5swGªô”ÌGH
9(:
ð8-kø
__2
! XMM`!XN$R%,XRY:
XY(!e+a:T(E(&/VI()2/6$I$2%K0/&52/) (K2%$G2/) I(2#/5 6/%2#(5(2(%I)$2/) /664)*G5(0%(054(0
) *)0()*(K2%$G29(:J//5 #(I!XMRM!RXR$Q%,\LN:
X\(!
M,~
!
t¼
!
MÔt
:
ðǑGH6r
e4-#-31
…©

9(:
TôðÇ
!XMMY!L$_%,X_:
XN(!?*4B() AT! .$) -=! 1(/=1!(2$&:>I4&2<%(054(I(2#/5
6/%2#(5(2(%I)$2/) /6XMQ V(02G5(0) %G(V$55(040)**$0
G#%/I$2/*%$V#B[I$000V(G2%/I(2%B9(:>)$&#I>G2$! XMMN!
YR` $R%,Y\:
X`(!
ë¼
!
:ž±
!
ò€º
!
‡
:
6þùjý$
<
Ij}ÿ
<
[ÿ…©
›N*^&ÔJKr
RX
¢ðÇGH
9(:
ðÇ__2
! XMMY!
N$_%,Q\R:
QM(!A$#P/4P a3! d$$2(%=J! 7$%A>:1I4&2$)(/405()26G$<
2/) $)5 ^4$)22$2/) /60(&(G2(5 /%*$)/G#&/%)(V(02G5(%(054(0
) #/)(BPB64&<0G$) *$0G#%/I$2/*%$V#B>)$&#I>G2$! XMMY!LLN $R[X%,YX:
QR(!
÷U
!
²)
!
¿‚y
:
r†Çr
_M
¢ðÇGH[Ij}ÿ
<
[ÿ6
9(:
9Ô^Nr’ÿ
! XMMN!QN$_%,L`:
QX(!
ƒð
!

!
„…ª
!
‡
:
Ij}ÿ
<
[ÿ¹“©&Ôvv¶
r
QX
¢GHðÇ
9(:
r†Ç
!XMMN!Q`$RM%,RLYN:
QQ(!
†ËG
!
ë<‡
!
œŸ
!
‡
:
Ij}ÿ
<
[ÿ©&ÔvF’Ç
ÁrèlºªðÇGH
9(:
ÇÌ6¥¦
! XMM\!X\$`%,
RQ_N:
Q_(!
ˆ‰
!
ÛUÎ
!
åÑ
!
‡
:@<=1
©Z9&ÔrÇÁr
X`
¢
ðÇGH·
9(:
v™Çø¡__2
! XMM\!X_ $XY%, Q_X!
Q\`:
QL(!
¤ÍZ
!
ŠøM
!
0L
!
‡
:
Ij}ÿ
<
[ÿ¹“©&Ô8,
$åÇ«W’rèlÏðÇGH
9(:
8,ø_û_2
!
XMMY!XX$
Ö©
%,_LR:
QY(!
‹KÎ
!
Œ®­
!
ˆt
!
‡
:
Ij}ÿ
<
[ÿ©&ÔUV¢‘¢èlÏðÇGH·
9(:
:ëä̃„i™€
!XMM`!
XR$X%,XY\:
Q\(!
ô²B
!
Ž
!
ŠøM
:
Ij}ÿ
<
[ÿ¹“©&ÔYZä
Q«W’rèlÏðÇGH
9(:
9µ­ú­Ç
! XMMN!R`
$_%,\NY:
QN(!
¿Þ!
ëCt
:
Ij}ÿ
<
[ÿ©Z9&ÔrÇrèlÏÑ
èl¿ðÇGH·
9(:
6&ç_2
!XMML!X_$Q%,`M:
Q`(!
D 
!
@Eï
!
ˆFs
!
‡
:
rÇÁrèlºªðÇ[
@<
?;<=1

9(:
:sð8ø_
! XMM`!RL$LL%,Q_:
_M(!
7‘A
!
”D
!
QΎ
:@<=1
J&r†ÇrGH[èlÏ
ðÇ
9(:
æ“ú_¥¦
!XMML!XR$Q%, QRL:
_R(!
U’K
!

!
DL
!
‡
:@6Ï\r
R¢èl
ºÑ9.³¶šðÇGH
9(:
‡_=^__2
! XMML! XY
$RX%,XXRN:
_X(!=(bG4$=! J(%(%! @$%Gl$<3(B(09J:>)$&B0(0/60(&(G2(5
)/)<$42#/%b(5 )0(G2G5(0) V(VV(%0PB*$0G#%/I$2/*%$V#B[
I$000V(G2%/I(2%B$)5 *$0G#%/I$2/*%$V#B[2$)5(I I$000V(G<
2%/I(2%B9(:J//5 #(I!XMM`!RRX $R%,XXR:
_Q(!@/)bo&(b<3/5%l*4(b3=! 3$&$&:T(2(%I)$2/) /6XQ V(02G5(%(054(0) &($6BE(*(2$P&(0
40)**$0G#%/I$2/*%$V#B/) 2%$V I$000V(G2%/I(2%B$)5 $)$&B2(
V%/2(G2$)209(:9#%/I$2/*%>! XMMN$RR`Y[RR`\%,RMM:
__(!@/)b$&(b<-*($J9! .(%)$)5(b&I$)0$$&:=$2%K<(6(G20/6E(*(2$P&(G/II/52(0) (&(G2%/2(G2/) $VV&(5 2/V(02G5(I4&2%(04($)$&B009(:9#%/I$2/*%
>! XMMX! `YY, RLL:
_L(!1G#()GW J9! C(#/2$B1 9:T/(064%2#(%G&($)<4V %(54G(2#(I$<
2%K()#$)G(I()2(6(G2) *$0G#%/I$2/*%$V#G$)$&B00/6V(02<
G5(%(054(0) 6//59(:9#%/I$2/*%>! XMMM! NYN, LR:
_Y(!.$H0&/E$9! d%/02&W/E$9:=$2%K(6(G20) $4&2%$%2%$G($)$&B00
/6V(02G5(%(054(0) 6//5 $)5 P/2GI$2%G(09(:9#%/I$<
2/*%>! XMMQ! RMMM, RNR:
_\(!/)04(&/1 7! 7($2%b>! @(%I$) =! (2$&:T(2(%I)$2/) /6
V(02G5(%(054(0PB@<=1 40)*$)$&B2(V%/2(G2$)202/G/4)2(%<
$G22#(I$2%K(6(G29(:>)$1G! XMML!XR,RX`R:
-``Q-
{
QY
ï{
_
—
XMRR
÷
X
´
!!!!!! ! ! ! ! ! !!!! ! ! ! !
U/&fQY! ;004(!_
J(P%4$%B! XMRR
6HR/CUAK0CHADAG.0C/D0BCBM.I1D0-GAK0HIANAKD0U0HAK0CDG/H0D0BC/1
2E0CAKA.AH0U0CALF W2->=
C;,T/)*H)*! +,-9$)
!
! c,+$/P/
$;$%21(1/#31,)-8F13%#9#%12#1(41G%20 C2%-2 F13%#? ;-9101E2(!%!+!1-8F13%#%29
492!D1<19-.,12!! @1%B%20 RMMR`Q! ;$%2%
6LKDG/UD(!A#(G4%()2I(2#/50/6V%(V$%$2/) /6V(02G5(%(054($)$&B00) 2%$52/)$&#)(0(I(5G)(F(%(04II$%b(5 )
2#0V$V(%:>)5 2#()(FV%(V$%$2/) 2(G#)^4(040(5 ) %(G()2B($%0F(%(%(E(F(5! F#G# )G&45(5 0/&5$18=-%! e4-.-31!I$2%K0/&5) 2#(2%$52/)$&#)(0(I(5G)(F(%($&0/)G&45(5 ) 2#(V$V(%!$)5 $)$&B0(5 2#(V%/P&(I) 2#(5(2(%I)$2/) P$0(5 /) 2#(G#$%$G<
2(%02G0/6A=0:
A`F TBGHK(!2%$52/)$&#)(0(I(5G)(& I4&2<%(054(V(02G5(& @<=1& 5(2(%I)$2/)& V%(V$%$2/):
HB0,!+a%#)QU[U..#+!!+%+$
$
‘$Q
!
—˜™
%
&
œXž

Ÿ ¡¢£¤¥¦§¨©J>ª«•Ž¬­
òóôÿ˜¡MlrÇÁg|
!
GÚ÷;êrú8Γ•áÖS7
#
ÜÝ
#

#

#
¨$
#
“#‡Ÿ)ßK

I•òó
ôµl”g
!
 -_ê•1il–²“
!
—†ÁLY`“Yµ
!
ªñ•[úL¿ãAõàiYꡘ²)ï

XM
™ö
NM
÷ô™š
!
ò­™š¡ÓƕEuò¿]ùÓ
!
>6“&{„ô-)-7pÿòó™•çùÓ
!
Íò­òóô
[ä·è&G¤þ(Öz

 -b|òó
!
a&š›|8ò
!
ájÀãuò¡fTg

Tô¿]ùÓ[öGi•çùÓ
[€F
!
Í|8ò|÷äK[òóôjЕ -š›
XYM
8uò$[òóô

uò¿]œ‚_Cò­Àãuòãî`
&¤÷[Aw
2
ê&J°
#
 ¤
#

#

#
$%ÚÁ÷;rú\“òóôEËúL¿ãAõ[ï«
#
ͧ
#
…©
!
Íòóôi{Eҗ
†ÁLæ
!
ÅömÁL“µ
#
“÷òóô
!
êò­ÁL[õ‡ã

C;*ðÇ812è&˜¾Ôi
*
rú¥¦
+#
*
r­rÇ¥¦
+
¹Äˆ_
.
;*ðñ
/
òóôúL¿ãAõøö÷Eèøí7¡ù

Rf
í74Ò
,
òóô[¿¢úL¿ãAõ\“…©
#
ͧ
#
ï«
#
Ù‡

Xf
í7&
,
mN
#
çž
#
ø_
!
9Ÿ7ž&|‚DL|“©L|Ÿ)
!
8(YŸ 
R LMM
8

Qf
!cï
,
?.EFLM
#
€
#
€P
#
Q(
#
HI
#
/U
#
/0‡¹H…š

_f
g9’
,XMRR
÷
_
´
QM
§

Lf
øuá/
,
|‡ø
L
M
!
øt
Q MMM
:Goa
R QNN
:òóô| 
&
ý‡ø
RM
M
!
øt
R MMM
:Goa
R QNN
:òóô| 
&
„‡ø
QM
M
!
ø¡oa
R QNN
:òóô| 
&
–|ø¢)M
!
ø¡oa
\NN
:òóô| 

Yf
bøMHX]
XMRR
÷
Y
´]
*
rú¥¦
+#*
r­rÇ¥¦
+
€y

\f
bøEBÄÁ;úC;*ðÇ812è&˜
!
»šKÄ
*
òóô¿ãäÒ
+
X†9IEFÏ£ÍÈ
X
Ù

Nf
!n1
,FBbRL`N]0/#4:G/I
`f
{p/0
,$MRM%L`QLXYL_
-MM_-
{
QY
ï{
_
—
XMRR
÷
X
´
!!!!!! ! ! ! ! ! !!!! ! ! ! !
U/&fQY! ;004(!_
J(P%4$%B! XMRR