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Studies on chemical constituents of Uvaria tonkinensis var. subglabra

紫玉盘属植物乌藤化学成分研究


目的:分离鉴定乌藤中化学成分。方法:采用各种色谱法进行分离,运用多种波谱方法鉴定化合物结构。结果:分离并鉴定了7个化合物,分别是乌藤素 C(1),β senepoxide(2),2,4 二羰基六氢 1,3 二氮杂卓(3),山柰酚 3,7 O α L 二鼠李糖苷(4),安诺洛宾(anolobine,5),(-) lyoniresinol(6)和schizandriside(7)。结论:化合物1是新化合物,化合物2~7为首次从该植物中分离得到。

Objective: To isolate and identify chemical constituents of Uvaria tonkinensis var. subglabra.  Method: The column chromatographic techniques were applied to isolate constituents, and their structures were elucidated by means of spectral data analysis including 1D and 2D NMR, IR and MS techniques.  Result: Seven compounds were isolated and identified as subglain C (1), β senepoxide (2),  2, 4 dioxohexahydro 1, 3 diazepin (3), kaempferol 3, 7 di O α L rhamnoside (4), anolobine (5), (-) lyoniresinol (6) and schizandriside (7).  Conclusion: Compound 1 was the new natural product; compounds 2 7 were isolated for the first time from U. tonkinensis var. subglabra.