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期 刊 ：中国中药杂志 2006年 31卷 04期 页码：309.

关键词：白云花；化学成分；香豆素；双香豆素；

Keywords:Heracleum rapula, constituents, coumarin, bicoumarin,

摘 要 ：目的:研究白云花根的化学成分。方法:用各种现代色谱方法分离白云花根化学成分,用波谱技术(IR,UV,MS,1D和2D NMR)鉴定结构。结果:从白云花根中分离得到8个香豆素类成分,分别鉴定为甲氧基欧芹酚(ostholⅠ),佛手苷内酯(bergaptenⅡ),花椒毒素(xanthotoxinⅢ),异虎耳草素(isopimpinellinⅣ),欧前胡素(imperatorinⅤ),异欧前胡素(isoimperatorinⅥ),cnidilinⅦ,珊瑚菜内酯(phellopterinⅧ)。1个双香豆素类成分,鉴定为rivulobirinA(Ⅸ)。结论:其中Ⅵ,Ⅶ,Ⅷ,Ⅸ等4个成分为首次从该植物中分离。

Abstract:Objective: To study the chemical constituents in roots of Heracleum rapula.Method: The constituents were isolated by column chromatography on silica gel and ODS,and identified by spectroscopic methods.Result: Nine compounds,osthol(Ⅰ),bergapten(Ⅱ),xanthotoxin(Ⅲ),isopimpinellin(Ⅳ),imperatorin(Ⅴ),isoimperatorin(Ⅵ),cnidilin(Ⅶ),phellopterin(Ⅷ),rivulobirin A(Ⅸ) were isolated and identified.Conclusion: Compounds Ⅵ,Ⅶ,Ⅷ,Ⅸ were isolated from this plant for the first time.

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