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期 刊 ：中国中药杂志 2007年 32卷 08期 页码：722.

关键词：麦当乳通颗粒；左旋多巴；催乳作用；催乳素；

Keywords:Maidang Rutong granule, l-dopa, galactagogue, prolactin,

摘 要 ：目的：研究麦当乳通颗粒对哺乳期大鼠的催乳作用。方法：采用母大鼠腹腔注射左旋多巴建立乳汁分泌不足的模型,观察不同剂量的麦当乳通颗粒对哺乳期缺乳母大鼠泌乳量、血清催乳素和乳腺组织的影响,以及对乳鼠生长的促进作用。结果：麦当乳通颗粒可显著增加缺乳母大鼠的泌乳量,可显著对抗左旋多巴引起的母鼠血清催乳素减少,明显对抗左旋多巴引起的大鼠乳腺萎缩,并显著提高其所喂养的仔鼠体重增加率。结论：麦当乳通颗粒对左旋多巴诱发哺乳期大鼠缺乳有明显的催乳作用。

Abstract:Objective: To study galactagogue effect of Maidang Rutong granule on the lactation rats. Method: The experiments were designed to observe the efficiency of Maidang Rutong granule on lactescence, serum prolactin, and morphology of mammary gland with rat galactozemia model established by injecting l-dopa. Result: Maidang Rutong granule showed significant enhancement for lactescence and the offspring‘s body weight. It could antagonize the decrease of serum prolactin and the atrophy of mammary gland induced by l-dopa. Conclusion: Maidang Rutong granule exhibited significant galactagogue effect on the l-dopa-induced galactozemia in rats.

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