Abstract:Extraction,purification and determination methods of glycyrrhizic acid in Licorice are surveyed in this paper.The extracting efficiency of dilute ethanol solvent for glycyrrhizic acid is higher than water extraction,and ammonia appended to ethanol solution can increase the effect of extraction.Ultrasound method,microwave-assisted method and supercritical CO_(2) fluid extraction are more effective than the conventional techniques,due to the short extraction time,low consumption of solution and energy.The modern analytical methods such as TLCs,HPLC and CE can determine the content of glycyrrhizic acid rapidly and exactly.