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期 刊 ：中国中药杂志 2008年 33卷 16期 页码：1990.

关键词：木樨科；梣属；秦岭白蜡树；化学成分；

Keywords:Oleaceaue, Fraxinus, Fraxinus paxiana, chemical constituents,

摘 要 ：目的：研究木樨科梣属秦岭白蜡树Fraxinus paxiana的化学成分。方法：应用色谱技术进行分离和纯化，通过波谱方法鉴定其化学结构。结果：从陕西秦皮的甲醇提取物中分离得到15个化合物，分别鉴定为秦皮甲素(esculin，1)，秦皮乙素(esculetin，2)，梣皮苷(fraxin，3)，梣皮素(fraxetin，4)，毛柳苷(salidroside，5)，osmanthuside H(6)，松脂醇-4,4′-二-O-β-D-葡萄糖苷(liriodendrin，7)，3-(4-β-D-葡萄糖基-3-甲氧基)-苯-2-反式-丙烯酸［3-(4-β-D-glucopyranosyloxy-3-methoxy)-phenyl-2E-propenol，8］，threo-syringylglycerol(9)，euscaphic acid(10)，3-羟基-1-(4-羟基-3, 5-二甲氧基苯)-1-丙酮(3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-propanone，11)，3-羟基-1-(4-羟基-3-甲氧基苯)-1-丙酮(ω-hydroxypropioguaiacone，12)，芥子醛(sinapyladehyde，13)，白桦酯酸(betulinic acid，14)和甘露醇(mannitol，15)。结论：化合物8～12为首次从该属植物发现，其他化合物均为首次从该植物中分离得到。

Abstract:Objective: To investigate the chemical constituents of Fraxinus paxiana. Method: The chemical constituents were isolated and purified by chromatographic techniques and the structures of the compounds were identified with or by spectroscopic methods. Result: Fifteen compounds were obtained from the methanol extract of F. paxiana and their structures were elucidated as esculin (1), esculetin (2), fraxin (3), fraxetin (4), salidroside (5), osmanthuside H (6), liriodendrin (7), 3-(4-β-D-glucopyranosyloxy-3-methoxy)-phenyl-2E-propenol (8), threo-syringylglycerol (9), euscaphic acid (10), 3-hydroxy-1-(4-hydroxy-3, 5-dimethoxyphenyl)-1-propanone (11), ω-hydroxypropioguaiacone (12), sinapyladehyde (13), betulinic acid (14) and mannitol (15). Conclusion: All compounds were obtained from this plant for the first time.

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