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期 刊 ：中国中药杂志 2006年 31卷 08期 页码：653.

关键词：六味地黄丸；丹皮酚；超临界CO2萃取；

Keywords:Liuwei Dihuang pill, paeonol, supercritical fluid extraction,

摘 要 ：目的:研究中药复方制剂中有效成分提取分离方法。方法:用超临界流体萃取六味地黄丸中的丹皮酚,HPLC用于分析提取物。结果:夹带甲醇(流速0.4 mL.min^-1)的超临界CO₂能有效地提取六味地黄丸中的丹皮酚。结论:该分析方法具简便、快速、准确的优点。

Abstract:Objective: To study the method of extraction of active ingredient from complex Chinese patent medicine.Method: Supercritical fluid extraction(SFE) has been used to extract paeonol from Liuwei Dihuang pill and HPLC was used to analyze the extracts.Result: The methanol modified supercritical CO^-1(0.4 mL·min^-1)can effectively extract paeonol from Liuwei Dihuang pill.Conclusion: SFE-HPLC method of off-line for analysis of extract was simple,quick and accurate.

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