Abstract:Objective: To optimize the extraction conditions of Dandelions (Taraxacum Weber). Method: Using the uniform design, the content of total fkvonoids and quercetin were detected to investigate the extraction process of Dandeh‘ons. Result: The ethanol concentration and the ethanol volume in the uniform test impacted the test mostly. The best extraction process of Dandeh‘ons was obtained as following: 13 times of 85% ethanol as the solvent, extraction for 2 times and 1h for each time. Conclusion: The extraction ratio of total flavonoids and quercetin are higher according to the above extraction process.