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期 刊 ：中国中药杂志 2003年 28卷 02期 页码：138.

关键词：球蕊五味子；化学成分；五环三萜酸；

Keywords:Schisandra sphaerandra, chemical constituents, pentacyclic triterpene carboxylic acid,

摘 要 ：目的:提取、分离、鉴定球蕊五味子藤茎化学成分。方法:乙醇冷浸提取,石油醚和乙酸乙酯依次萃取,硅胶柱层析分离纯化,通过理化常数和光谱分析鉴定其化学结构。结果:分离鉴定了12个化合物,分别为五味子丙素(1),甘五酸(2),nigranoic acid(3),儿茶素(4),2a,24-二羟基乌索酸(5),3-乙酰氧基乌索酸(6),乌索酸(7),26-羟基二十六烷酸甘油酸酯(8),二十六烷酸甘油酯(9),脂肪酸(10),β-谷甾醇(11),胡萝卜苷(12)。结论:3个五环三萜酸类化合物为首次从五味子科中分离得到。

Abstract:Objective: To investigate the chemical constituents from the stems of Schisandra sphaerandra. Method:Compounds were isolated from ethanolic extract of the titled herb by silica gel column chromatography, and their structures were elucidated by physical and chemical evidences and spectroscopic analysis. Result: 12 compounds were obtained and identified as wuweizisu C (1), ganwuweizic acid (2), nigranoic acid (3), catechin(4), 2a,24-dihytroxyursolic acid. (5), 3β-O-acetylursolic acid (6), urso-lic acid(7), slyceryl26-hydroxyhexacosanoate(8), slyceryl hexacosanoate (9), fat acids (10), β-sitosterol(11), daucosterol (12), respectirely. Conclusion: Three pentacyclic triterpene carboxylic acid (5-7) were isolated from Schisandreae for the first time.

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