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期 刊 ：中国中药杂志 1998年 23卷 12期 页码：746.

关键词：银杏；多糖；SOD；MDA；自由基；

Keywords:Ginkgo biloba, polysaccharide, SOD, MDA, free radical,

摘 要 ：目的:观察银杏外种皮多糖(GBEP)对不同状态小鼠血清SOD和MDA形成的影响。方法:用GBEP给荷瘤小鼠、环磷酰胺(CTX)抑制小鼠及正常小鼠灌胃给药,检测小鼠血清中的SOD活性及MDA含量。结果:GBEP可明显提高荷瘤小鼠血清SOD活性,并能降低其MDA含量,也能改善CTX抑制小鼠的上述指标,但对正常小鼠则无明显影响。结论:GBEP可促进机体在病理状态下的自由基清除能力。

Abstract:Objective:To study the influence of Ginkgo biloba exocarp polysaccharides(GBEP) on serum superoxide dismutase(SOD) activity and malondialdehyde(MDA) level in mice under different states.Method:GBEP was orally administrated to S₁₈₀bearing mice,cyclophosphamide(CTX) intoxicated mice and normal mice.The contents of SOD and MDA in the mice‘s blood were checked.Result:GBEP significantly enhanced SOD activity and decreased MDA content in S180 bearing mice.Similar effects were observed in CTX intoxicated mice.In normal mice,however, no such effects were observed.Conclusion:GBEP may modulate the free radical system in mice under abnormal states.

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