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期 刊 ：中国中药杂志 1998年 23卷 07期 页码：432.

关键词：芍药汤；配伍变化；薄层扫描；含量测定；

Keywords:Shaoyao decoction, compatibility change, TLC-scanner, content determination,

摘 要 ：目的：探讨中药复方配伍化学成分相互作用的一般规律。方法：用薄层扫描法测定了芍药汤中黄连、大黄、黄芩之有效成分在不同配伍情况下煎液中的含量。结果：大黄、黄芩、甘草可使黄连中小檗碱含量明显降低，尤以大黄最为严重。黄连亦可明显降低各酸性成分含量。结论：各酸性成分之间相互影响，使所测成分含量降低。

Abstract:Objective:To probe the regular patterns of interactions among chemical components in Chinese medicinal complex prescriptions Method: The active components of Rhubarb,Coptis root and Baikal skullcap root in different patterns of compatibility were determined by TLC-scannerResult:The berberine content in Coptis root can be decreased obviously by Rhubarb,Baikai skullcap root and Licorice root,especially by RhubarbCoptis root can also decrease the contents of acid components Conclusion:The acid components can affect each other, thus reducing the contents of effective components.

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