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期 刊 ：中国中药杂志 1998年 23卷 06期 页码：363.

关键词：叶下珠；化学成分；抗病毒；去氢诃子次酸甲酯；短叶苏木酚酸甲酯；

Keywords:Phyllanthus urinaria, constituents, antivirus, methyl ester dehydrochebulic acid, methyl brevifolin carboxylate,

摘 要 ：对大戟科叶下珠属植物叶下珠的干燥全草进行了化学成分及其抗乙肝病毒活性的研究，共分得１１个化合物，其中２个新化合物为去氢诃子次酸甲酯、短叶苏木酚酸甲酯。通过抗病毒、抗乙肝表面抗原及保肝试验，肯定了叶下珠的抗乙肝病毒活性。

Abstract:Studies on the chemical constituents of Phyllanthus urinaria and its antiviral activity against hepatitis B virus were completed. Eleven compounds have been isolated. Two of them are new compounds methyl ester dehydrochebulic acid and methyl brevifolin carboxylate. Antiviral experiments on HBsAg in vitro and liver damage caused by CCl 4 have shown that.Phyllanthus urinaria possesses antiviral activities against HBV.

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