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期 刊 ：中国中药杂志 1998年 23卷 09期 页码：539.

关键词：牡蛎；配伍；浸出效果；

Keywords:Concha Ostreae, compatibility, leaching effect,

摘 要 ：目的:以牡蛎为石性药代表作研究对象,为合理掌握石性药的浸出方式提供参考。方法:以配伍浸出变化率及A值变化率为指标,考察其对同一处方中熟大黄、黄芩、蒲黄、枳实4味药材配伍浸出效果的影响。结果:牡蛎与这几味药材共煎,可在一定程度上降低浸出物收率,但不会引起熟大黄、枳实指标成分的损失,仅对黄芩甙的含量有一定影响。结论:牡蛎浸出方式的选择,宜考虑处理好工艺与剂型的关系。

Abstract:Objective:Based on a study of Concha Ostreae,to provide some reference for the rational approach to leaching mineral drugs.Method:Taking the change rates of compatible leaching and value of A as targets,the compatible leaching effect of Concha Ostreae with Radix et Rhizoma Rhei Praeparata,Radix Scutellariae, Pollen Typhae and Fructus Aurantii lmmaturus was studied.Result:If Concha Ostreae and the above cited medicinal herbs are decocted together,the yield of extract may be reduced to a certain extent,but the target composition of Radix et Rhizoma Rhei Praeparata and Fructus Aurantii lmmaturus remains intact,only the content of Radix Scutellariae baicalin may be influenced.Conclusion:The relationship of technology with preparation must be taken into consideration when making choice of the proper way to leach Concha Ostreae.

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