Abstract:Objective: To observe the effects of antioxidation and ceramide content of improved prescription of Didang-tang (IPDT) on exprimental atherosclerosis(AS) rabbits. Method:Plasm Superoxide Dismutase(SOD) activity was detected with micro-content fast detecting method, Plasm Malondialdehyde (MDA) content with improved BaMuGuoFu method, and Aortic Ceramide (CER) content with thinlayer scannig. Result: IPDT could effectivly improve plasma SOD activity and decrease plasma MDA contrnt and decrease aortic CER content. Conclution:IPDT on exprimental AS is related to the improvement of antioxidation and decrease of CER content.