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期 刊 ：中国中药杂志 1993年 18卷 04期 页码：240.

关键词：四君子汤；淋巴细胞增殖；迟发型皮肤超敏反应；溶血素；骨髓细胞；

Keywords:Sijunzi decoction, proliferation of lymphocyte, DCH, hemolysin, hone marrow cells,

摘 要 ：四君子汤、四物汤和八珍汤均能对抗HC对体外淋巴细胞增殖的抑制作用,以四君子汤作用为好。四君子汤尚能对抗CY对DNCB所致DCH反应及溶血素生成的抑制作用。3方皆能提高CY所抑制的碳粒廓清速率和骨髓细胞数,仍以四君子汤为优。

Abstract:Sijunzi decoction, Siwu decoction and Bazhen decoction can antagonize the suppressive effect of hydrocortisone on proliferation of lymphocyte by spleen ceils in C₅₇BL/6J mice in vitro, and of the three decoctions Sijunzi works best. Sijunzi Decoction can antagonize the suppressive effect of cyclophosphamide on the delayed cutaneous hypersensitivity (DCH) induced by DNCB in mice and the production of hemolysin in mice immunized with SRBC. The three prescriptions all can enhance the clearance rate of iv charcoal particles as well as bone marrow cells inhibited by cyclophosphamide in mice, but Sijunzi decoction functions best of all.

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