Abstract:The patients with chronic superficial gastritis were perfused in the stomach with 20g of Dendrobium nodile to ob-serve the variations in gastric acidity output ,serum gastrin and plasma somatostatin concentration. The result showed asignificant increase in both acidity output and serum gastrin concentration (P<0 .01 ) . No significant change occurredin plasma somatostatin concentration (P>0. 05 ).