Abstract:The weights of seminal vesicle and prostate gland of castrated young rats were significantly in-creased by administration of alcoholsoluble extract from decoction of Cistanche deserticola.The weights of testes,seminal vesicle and prostate gland in mice and rats were also increased by the extract.The phagocytic function of intra-abdominal macrophage in mice was activated by decoction of Cistanche deserticola.The results showed no sta-tistical diferences between crude and prepared drugs.The maximum oral tolerance for mouse was 40g/kg.