Abstract:The quality of astragalus membranaceus was studied with the treatment of Astragalus membranaceus seed coating by different concentrations (2%, 4%, 6% and 8% of seed dry weight), ND general seed coating (8% of seed dry weight) and seed uncoated. The contents changes of astragaloside Ⅳ, total flavonoids and pesticide reside were analyzed.The results indicated that treated by astragalus membranaceus seed coating. It could both improve the main active component-astragaloside Ⅳ and total flavonoids in radix astragali, and the pesticide residue of seed coating could be fully degradationed with the grow of plants. Proved that seed coating can improve quality of A. membranceus(Fisch) Bge.