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期 刊 ：中国中药杂志 2008年 33卷 16期 页码：1988.

关键词：化学成分；结构鉴定；丽江獐牙菜；走胆草；

Keywords:chemical constituents, structure identification, Swertia delavayi,

摘 要 ：目的：对龙胆科獐牙菜属植物丽江獐牙菜Swertia delavayi全草乙醇提取物进行研究。方法：经反复纯化制备化合物,并根据化合物的理化性质分析、波谱解析、对照品比较及与文献报道对比鉴定化合物的化学结构。结果：从95%乙醇室温提取物中分离得到7个化合物,分别鉴定为齐墩果酸(oleanolic acid，1)，龙胆苦苷(gentiopcroside，2)，獐牙菜苦苷(swertiamarin，3)，胡萝卜苷(daucosterol，4)，1,3,8-三羟基-2,5-二甲氧基酮(swertiadecoraxanthone-Ⅱ，5)，异牡荆苷(isovitexin，6)，异红草苷(isoorientin，7)。结论：化合物2～7为首次从该植物中分离得到,且化合物6为首次从该属植物中分离得到。

Abstract:Objective: To isolate and identify the chemical constituents of 95% alcohol extract from Swertia delavayi. Method: The compounds were isolated and purified by column chromatogrphy and their structures were identified by the physicochemical properties and spectral analyses. Result: Seven compounds were isolated and identified as oleanolic acid (1), gentiopcroside (2), swertiamarin (3), daucosterol (4), swertiadecoraxanthone-Ⅱ (5), isovitexin (6), isoorientin (7). Conclusion: Compounds 2-7 were isolated from S. delavayi for the first time. While the compound 6 was firstly reported from the genus Swertia.

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