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期 刊 ：中国中药杂志 2007年 32卷 12期 页码：1182.

关键词：积雪草；阿魏酸酯；三萜；

Keywords:Centella asiatica, docosyl ferulates, triterpene,

摘 要 ：目的：研究积雪草中的化学成分。方法：以硅胶、凝胶等多种柱色谱分离,制备高效液相色谱纯化,以波谱方法鉴定结构。结果：分离得到5个化合物,鉴定为阿魏酸二十二酯(1),bayogenin(2),3β-6β-23-trihydroxyolean-12-en-28-oic acid(3),3β-6β-23-trihydroxyurs-12-en-28-oic acid(4),D-gulonic acid(5)。结论：所有化合物均为首次从积雪草属植物中分离得到。

Abstract:Objective: To study the chemical constituents from Centella asiatica. Method: Chemical constituents were isolated by repeated column chromatography (Toyopearl HW-40C and HPLC) and their structures were elucidated on the basis of spectroscopic method. Result: Five compounds were identified as: docosyl ferulates (1), bayogenin (2), 3β-6β-23-trihydroxyolean-12-en-28-oic acid (3), 3β-6β-23-trihydroxyurs-12-en-28-oic acid (4), D-gulonic acid (5). Conclusion: All of the Compounds were isolated for the first time from C. asiatica.

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