Abstract:Objective: To explore the effects of xue-bao capsules on injury of radio-or chemo-therapy in mice,in order to provide rationale behind clinical trials. Method: xue-xu (deficiency of blood) model in mice was induced by radiation or cyclophosphamide. Leucocyte (WBC), erythrocyte(RBC), hemoglobin(Hb) and pletelet(Pt) in peripheral blood as well as CFU-E and CFU-Gm in bone marrow were counted. Result: CFU-E and CFU-Gm in normal mice were promoted by this drug. The reduction of WBC,RBC and Hb in peripheral blood as well as CFU-E and CFU-Gm in bone marrow owing to the 3.5 Gy of 60Co radiation were antagonized by the durg. It had also antagonized cyclophosphamide induced the reduction of WBC, RBC and R in peripheral blood. Conclusion: xue-bao capsules has the effects against the adverse reactions of radio-or-chemo-therapy.