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期 刊 ：中国中药杂志 2005年 30卷 11期 页码：842.

关键词：银合欢；总黄酮；降血糖；药理作用；

Keywords:Leucaena, total flavonoids, hypoglycemic efiect, pharmacodynamics,

摘 要 ：目的:探讨银合欢种子总黄酮(TF)的降血糖作用。方法:采用四氧嘧啶糖尿病小鼠模型以及由肾上腺素和葡萄糖引起的高血糖小鼠模型,观察TF对实验动物的降血糖效果。结果:TF对四氧嘧啶所致糖尿病小鼠有明显的治疗效果,对肾上腺素和葡萄糖引起的高血糖模型小鼠也有明显的降血糖作用,但对正常小鼠血糖无明显影响。结论:TF对高血糖模型小鼠有明显的降血糖作用,但对正常小鼠血糖无明显影响。

Abstract:Objective: To study the hypoglycemic effect of the total flavonoids in Leucaena seeds(TF). Method: Experimental observation was perfonned by using various diabetic mice induced by alloxan, adrenalin, etc. Result: TF could significantly lower the blood glucose levels in Alloxan model mice, adrenalin model mice and hyperglycemic mice, while had no hypoglycemic effect on the normal mice. Conclusion: The total flavonoids in Leucaena seeds has hypoglycemic effect in diabetic model mice.

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