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期 刊 ：中国中药杂志 1998年 23卷 11期 页码：671.

关键词：中药制剂；工艺；物理化学变化；

Keywords:Traditional Chinese Drugs, the technologies of preparing, the physicochemical changes,

摘 要 ：目的:根据文献综述中药在制剂工艺过程中的物理化学变化,为提高中成药的内在质量提供帮助。方法:按提取分离、浓缩干燥、成型等制剂工艺步骤,分别介绍沉淀反应、增溶作用、水解反应、氧化-还原反应等主要物理化学变化及其制剂学意义。结果与结论:开展制剂工艺过程中的物理化学变化及其机理的研究,对于完善中药学的理论基础,促进中药复方配伍理论的发展,提高中药制剂工艺的设计水平及中成药的内在质量,都有重要意义。

Abstract:Objective:Summarizing the physicochemical changes in the process of preparing traditional Chinese drugs and affording useful clues for the quality improvement of Chinese patent drugs.Method:Introducing the main physicochemical changes,such as precipitating reaction,solubility increasing,hydrolysis,and oxidation reduction etc.,which occur in the process of extracting,separating, concentrating and drying.Result and Conclusion :The research of physicochemical changes occurring in the process of preparation and the probe into their mechanism play an important role in perfecting the basic theories of Chinese pharmacy ,promoting the development of compatibility theory of Chinese pharmary and improving the technology design for preparing and controlling the quality of Chinese patent drugs.

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