Abstract:The rise of total lipid, triglyceride and total cholesterol, and the drop of cortisol in serum induced by PA can be significantly inhibited by total ginsenosides in the leaves of Panax ginseng [GSL, 60 mg/(kg·d)]. From GSL ten compounds have been isolated and identified as ginsenoside-Rb2,-Rc,-Rd,-Re,-Rg1-F3,F2,-Rg2,20(R)-Rg2 and -Rh1,respectively. Pharmacological study has proved ginsenoside-Re to be the chief active constituent of GSL.