Abstract:Objective:To compare the guanosine contents in various products of Pinellia Rhizoma processed by different amounts of ginger and alum.Method:Using the technology of HPLC.Result:The guanosine contents in the two pro ducts of Pinellia Rhizoma processed in line with the pharmacopoeial method and orthogonal method respectively are very close to each other and changevery little as compared with raw Pinellia Rhizoma.But the contents in the products of Pinelliae Rhizoma processed in other ways (digged in alum solution or in ginger Juice decocted with ginger juice,etc.) are much less than those of raw Pinellia Rhizoma.Conclusion:There are no obvious differences in guanosine contents between Pinellia Rhizoma processed by orthogonal technology and Pinellia Rhizoma processed by pharmacopoeial method.Processing technology has considerable influence on the water soluble components of Pinellia Phizoma.