Abstract:The results were obtained by oral administration of the decoction of Codonopsis pilosula in three different doses(10g,20g,40g) to 5 dogs with Heidenhain pouch.No significant changes occurred in the acidity output of Heidenhain pouch and plasma somatostatin concentration out of the oral administration (P>0.05).A significant increase occurred in serum gastrin concentration (P<0.05 or P<0.01)150min after a dose of 10g,90min and 150min after doses of 20g,and 30min,60min,and 150min after doses of 40g.